Blockade of alpha 4 beta 1-integrin-fibronectin adhesive interactions prevents chronic allograft rejection in sensitized recipients

Transplant Proc. 1998 Jun;30(4):939-40. doi: 10.1016/s0041-1345(98)00099-2.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alternative Splicing
  • Amino Acid Sequence
  • Animals
  • Cell Adhesion / drug effects
  • Cell Adhesion / immunology*
  • Fibronectins / antagonists & inhibitors*
  • Fibronectins / biosynthesis
  • Fibronectins / chemistry
  • Genetic Variation
  • Graft Rejection / immunology*
  • Graft Rejection / prevention & control*
  • Heart Transplantation / immunology*
  • Integrin alpha4beta1
  • Integrins / antagonists & inhibitors*
  • Integrins / immunology
  • Male
  • Molecular Sequence Data
  • Peptide Fragments / immunology
  • Peptide Fragments / pharmacology*
  • Polymerase Chain Reaction
  • Rats
  • Rats, Inbred BN
  • Rats, Inbred Lew
  • Rats, Sprague-Dawley
  • Receptors, Lymphocyte Homing / antagonists & inhibitors*
  • Receptors, Lymphocyte Homing / immunology
  • Receptors, Very Late Antigen / immunology
  • Recombinant Proteins / biosynthesis
  • Recombinant Proteins / chemistry
  • Skin Transplantation / immunology*
  • Transplantation, Heterotopic
  • Transplantation, Homologous

Substances

  • Fibronectins
  • Integrin alpha4beta1
  • Integrins
  • Peptide Fragments
  • Receptors, Lymphocyte Homing
  • Receptors, Very Late Antigen
  • Recombinant Proteins