A 37-year-old male was referred to our hospital with symptoms suggesting pneumonia. The preoperative diagnosis was primary lung cancer of the left upper lobe invading the distal aortic arch (DAA) (T4, stage IIIB). Complete resection was performed with associated resection of the pneumonectomy, DAA, and left subclavian artery. Dacron graft replacement was performed using ECC with selective cerebral perfusion. Histological examination revealed squamous cell carcinoma, n1 and negative surgical margins. We expect this patient to achieve long-term survival. We conclude that ECC with selective cerebral perfusion is both safe and effective for pulmonary surgery in cases with combined resection of the DAA.