Rapid detection of glyoxalase I (GLO) on cellulose acetate gel and the distribution of GLO variants in a Dutch population

Hum Genet. 1976 Sep 10;34(1):53-6. doi: 10.1007/BF00284434.

Abstract

A rapid electrophoretic procedure is described for detecting the human red cell glyoxalase I variants (GLO 1, GLO 2-1, and GLO 2) on cellulose acetate gel (cellogel) on which the sites of enzymed activity are visualized as purple bands against white background. The frequency of GLO1 gene in a Dutch population living in and around Leiden was found to be 0.4544.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Electrophoresis, Cellulose Acetate / methods
  • Gene Frequency
  • Genetic Variation*
  • Humans
  • Lactoylglutathione Lyase / blood*
  • Lyases / blood*
  • Netherlands
  • Phenotype

Substances

  • Lyases
  • Lactoylglutathione Lyase