Identification of lung regions in chest radiographs using Markov random field modeling

Med Phys. 1998 Jun;25(6):976-85. doi: 10.1118/1.598405.

Abstract

The authors present an algorithm utilizing Markov random field modeling for identifying lung regions in a digitized chest radiograph (DCR). Let x represent the classifications of each pixel in a DCR as either lung or nonlung. We model x as a realization of a spatially varying Markov random field. This model is developed utilizing spatial and textural information extracted from samples of lung and nonlung region-types in a training set of DCRs. With this model, the technique of Iterated Conditional Modes is used to determine the optimal classification of each pixel in a DCR. The algorithm's ability to identify lung regions is evaluated on a testing set of DCRs. The algorithm performs well yielding a sensitivity of 90.7% +/- 4.4%, a specificity of 97.2% +/- 2.0%, and an accuracy of 94.8% +/- 1.6%. In an attempt to gain insight into the meaning and level of the algorithm's performance numbers, the results are compared to those of some easily implemented classification algorithms.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Biophysical Phenomena
  • Biophysics
  • Diagnosis, Computer-Assisted / methods
  • Diagnosis, Computer-Assisted / statistics & numerical data
  • Humans
  • Lung / diagnostic imaging*
  • Markov Chains
  • Models, Theoretical
  • Neural Networks, Computer
  • Radiographic Image Enhancement / methods*
  • Radiography, Thoracic / methods*
  • Radiography, Thoracic / statistics & numerical data
  • Technology, Radiologic