Cutaneous Rosai-Dorfman disease

Clin Exp Dermatol. 1998 Jan;23(1):40-2. doi: 10.1046/j.1365-2230.1998.00312.x.

Abstract

We report a patient with purely cutaneous Rosai-Dorfman disease (RDD) who presented with a solitary, asymptomatic plaque on the back of her left thigh, with characteristic, large histiocytoid cells exhibiting emperipolesis histologically. Cutaneous lesions occur in 27% of patients with lymph node involvement in RDD however purely cutaneous disease has only been reported on 18 previous occasions. The aetiology is unknown, although it is though to be a reactive disorder rather than neoplastic, possibly an immunological response to an infectious agent.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Histiocytosis, Sinus / pathology*
  • Humans
  • Skin Diseases / pathology*
  • Thigh