Comparative investigation of the long non-coding M-F genome region of wild-type and vaccine measles viruses

Arch Virol. 1997;142(12):2521-8. doi: 10.1007/s007050050259.

Abstract

The sequence of the 300 nucleotides region of the measles virus genome was determined that includes a part of the 3'-untranslated region of the matrix (M) gene, the intergenic region and a part of the 5'-untranslated region of the fusion (F) gene [M-F region] for vaccine strain Leningrad-16 and 14 wild-type isolates. The data obtained demonstrate the variability of this long non-coding M-F region. No mutations in this region of the genome were found which seem to be specific for vaccine strains of measles virus (MV).

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Base Sequence
  • Chlorocebus aethiops
  • DNA, Viral
  • Genome, Viral*
  • Humans
  • Measles Vaccine / genetics*
  • Measles virus / classification
  • Measles virus / genetics*
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Homology, Nucleic Acid
  • Vero Cells
  • Viral Fusion Proteins / genetics*
  • Viral Matrix Proteins / genetics*

Substances

  • DNA, Viral
  • Measles Vaccine
  • Viral Fusion Proteins
  • Viral Matrix Proteins

Associated data

  • GENBANK/Y13677
  • GENBANK/Y13678
  • GENBANK/Y13679
  • GENBANK/Y13680
  • GENBANK/Y13681
  • GENBANK/Y13682
  • GENBANK/Y13683
  • GENBANK/Y13684
  • GENBANK/Y13685
  • GENBANK/Y13686
  • GENBANK/Y13687
  • GENBANK/Y13688