Abstract
We investigated the presence of human T-lymphotropic virus type 2 (HTLV-2) DNA in the peripheral blood mononuclear cell subsets obtained from 18 patients coinfected with human immunodeficiency virus type 1 and HTLV-2, 6 of whom also had predominantly sensory polyneuropathy (PSP). HTLV-2 DNA and RNA were found in CD8- and CD19-positive cells, and, for patients with PSP, in CD14-positive cells as well. Furthermore, the patients with PSP had higher proviral loads than those without PSP.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / virology*
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Adult
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DNA, Viral / blood
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Deltaretrovirus Antibodies / blood
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Evaluation Studies as Topic
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Female
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HIV-1*
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HTLV-II Infections / virology*
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Human T-lymphotropic virus 2 / genetics*
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Humans
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Macrophages / virology*
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Male
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Mathematical Computing
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Middle Aged
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Monocytes / virology*
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Peripheral Nervous System Diseases / complications
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Peripheral Nervous System Diseases / virology
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Polymerase Chain Reaction
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Proviruses / genetics*
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RNA, Viral
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Sensitivity and Specificity
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T-Lymphocyte Subsets / virology
Substances
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DNA, Viral
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Deltaretrovirus Antibodies
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RNA, Viral