Genetics and respiratory disease. 2. Alpha 1-antitrypsin deficiency, cirrhosis and emphysema

Thorax. 1998 Jun;53(6):501-5. doi: 10.1136/thx.53.6.501.

Authors

R Mahadeva¹, D A Lomas

Affiliation

¹ Department of Medicine, University of Cambridge, MRC Centre, UK.

No abstract available

Publication types

Review

MeSH terms

Dimerization
Genotype
Humans
Liver Cirrhosis / etiology*
Liver Cirrhosis / genetics
Liver Cirrhosis / metabolism
Mutation
Phenotype
Polymers
Pulmonary Emphysema / etiology*
Pulmonary Emphysema / genetics
Pulmonary Emphysema / metabolism
alpha 1-Antitrypsin / genetics
alpha 1-Antitrypsin / metabolism
alpha 1-Antitrypsin Deficiency / complications*
alpha 1-Antitrypsin Deficiency / genetics
alpha 1-Antitrypsin Deficiency / metabolism
alpha 1-Antitrypsin Deficiency / therapy

Substances

Polymers
alpha 1-Antitrypsin