Serum interleukin-6 in congestive heart failure secondary to idiopathic dilated cardiomyopathy

Am J Cardiol. 1998 Sep 1;82(5):688-90, A8. doi: 10.1016/s0002-9149(98)00388-9.

Abstract

Increased serum interleukin-6 (IL-6) was associated with a higher incidence of New York Heart Association functional classes III to IV and worse left ventricular function during follow-up. Patients with elevated serum IL-6 had poor prognosis. These results reinforce the concept that increased serum IL-6 may also play an important role in disease progression.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cardiomyopathy, Dilated / immunology*
  • Cardiomyopathy, Dilated / mortality
  • Female
  • Follow-Up Studies
  • Heart Failure / immunology*
  • Heart Failure / mortality
  • Humans
  • Interleukin-6 / blood*
  • Male
  • Middle Aged
  • Myocardial Contraction / physiology
  • Prognosis
  • Survival Analysis
  • Ventricular Dysfunction, Left / immunology
  • Ventricular Dysfunction, Left / mortality
  • Ventricular Function, Left / physiology

Substances

  • Interleukin-6