[Gaps: practical implications]

Arch Mal Coeur Vaiss. 1998 Mar:91 Spec No 1:41-51.
[Article in French]

Abstract

The French translations of the word "gap" include "hole, breach, opening". In the Anglo-saxon literature, the conduction gap or the gap phenomenon is defined as the period of the cardiac cycle during which a premature beat is blocked whereas more delayed or more premature beats are conducted. This rare phenomenon, observed mainly during extrasystolic stimulation, was previously called supernormal conduction. The underlying mechanism is distal block in the conduction system occurring when more premature beats lead to delay in the proximal conduction which gives the distal site time to become excitable again. The excitability gap is one of the main characteristics of reentrant arrhythmias. Its presence in a reentrant circuit ensures the regularity and stability of the arrhythmia. It also allows penetration of the circuit by external stimuli. This different extrasystolic stimulation technique (resetting) or rapid fixed rate pacing (entrainment) may be used diagnostically and therapeutically. It enables the identification of the arrhythmia circuit and a critical zone (protected isthmus, zone of slow conduction) which may constitute a target for ablation. It also offers a possibility for terminating the arrhythmia by external stimulation. Finally, the duration of the excitable gap may guide the choice of antiarrhythmic agent during pharmacological cardioversion of a reentrant tachycardia.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Arrhythmias, Cardiac / physiopathology*
  • Arrhythmias, Cardiac / therapy*
  • Electric Countershock*
  • Electrocardiography
  • Electrophysiology
  • Heart Conduction System / physiology*
  • Humans