Fulminant hepatic failure secondary to herpes simplex virus infection in a neonate: A case report of successful treatment with liver transplantation and perioperative acyclovir

H Egawa; Y Inomata; S Nakayama; A Matsui; H Yamabe; S Uemoto; K Asonuma; K Tanaka

doi:10.1002/lt.500040601

Fulminant hepatic failure secondary to herpes simplex virus infection in a neonate: A case report of successful treatment with liver transplantation and perioperative acyclovir

Liver Transpl Surg. 1998 Nov;4(6):513-5. doi: 10.1002/lt.500040601.

Authors

H Egawa¹, Y Inomata, S Nakayama, A Matsui, H Yamabe, S Uemoto, K Asonuma, K Tanaka

Affiliation

¹ Department of Transplant Surgery, Kyoto University Hospital, Kyoto, Japan.

PMID: 9791164
DOI: 10.1002/lt.500040601

Abstract

Neonatal disseminated herpes simplex virus (HSV) infection, including fulminant hepatic failure (FHF), is lethal, and the patients rarely have a chance for liver transplantation because of the rapid development of the disease. We describe of a case of FHF secondary to HSV infection in a neonate successfully treated by aggressive intensive care followed by liver transplantation.

Publication types

Case Reports

MeSH terms

Acyclovir / therapeutic use*
Antiviral Agents / therapeutic use*
Cytomegalovirus Infections / complications
Cytomegalovirus Infections / drug therapy
Female
Hepatic Encephalopathy / etiology*
Hepatic Encephalopathy / surgery*
Herpes Simplex / complications*
Herpes Simplex / drug therapy*
Humans
Infant, Newborn
Liver Transplantation*
Polymerase Chain Reaction

Substances

Antiviral Agents
Acyclovir