Prostate cancer in the elderly

Eur J Surg Oncol. 1998 Oct;24(5):379-83. doi: 10.1016/s0748-7983(98)92031-5.

Abstract

The incidence of prostate cancer is age related and increased longevity increases the number of elderly men with the disease. Management of prostate cancer in the elderly requires a different approach. Screening and aggressive case finding to seek out early confined disease are contraindicated in those with a life expectation below 10 years. Early confined disease in the elderly is usually managed expectantly. Hormone treatment is more appropriate for locally advanced disease, and is a valuable non-surgical treatment for bladder outflow obstruction due to prostate cancer. A significant proportion of elderly men with prostate cancer still die from other diseases. Hormone refractory disease in the elderly should be managed by palliation of symptoms rather than toxic second-line therapies. The aim always is diagnosis where appropriate, treatment which will be of benefit, and quality rather than length of life.

Publication types

  • Review

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Humans
  • Life Expectancy
  • Male
  • Middle Aged
  • Prostatic Neoplasms* / diagnosis
  • Prostatic Neoplasms* / therapy