Therapeutic effect of Xiaopiling Granules on gastric precancerous changes was observed, using image analyzer and electronic microscope. The result indicated that the Granules could efficiently eliminate gastric mucositis, nourish gastric mucosa, soften or restrain dysplasia, ameliorate structure atypism and cell atypism of dysplasia, promote elimination of dysplasia and efficiently ameliorate the ultrastructure of gastric precancerous changes.