The distribution of calcitonin gene-related peptide in gastric vagal circuit of rats

Anat Histol Embryol. 1998 Oct;27(5):331-3. doi: 10.1111/j.1439-0264.1998.tb00203.x.

Abstract

In the present study, we performed the retrograde tracing method using the neurotropic pseudorabies virus bartha strain (PRV-Ba) and immunohistochemistry against CGRP, to identify whether CGRP exists in the gastric monosynaptic vagal circuit between dorsal motor nucleus of vagus nerve (DMV) and nucleus tractus solitarius (NTS). At the results, PRV immunoreactive neurons were found in both DMV and NTS. However, CGRP-immunoreactive cells were present only in NTS, which contained no double-labeled neurons for PRV and CGRP. These results suggest that CGRP may not have a neuronal function in gastric vagal circuit of rat.

MeSH terms

  • Animals
  • Axonal Transport
  • Calcitonin Gene-Related Peptide / analysis*
  • Herpesvirus 1, Suid*
  • Immunohistochemistry
  • Neurons / cytology*
  • Neurons / physiology
  • Rats
  • Rats, Sprague-Dawley
  • Solitary Nucleus / anatomy & histology*
  • Solitary Nucleus / cytology
  • Solitary Nucleus / physiology
  • Stomach / innervation
  • Synapses / ultrastructure
  • Vagus Nerve / anatomy & histology*
  • Vagus Nerve / cytology
  • Vagus Nerve / physiology

Substances

  • Calcitonin Gene-Related Peptide