Practical synthesis of 2,6-dideoxy-D-lyxo-hexose ("2-deoxy-D-fucose") from D-galactose

Carbohydr Res. 1998 Aug;310(4):223-8. doi: 10.1016/s0008-6215(98)00160-8.

Abstract

2,6-Dideoxy-D-lyxo-hexose was prepared efficiently from D-galactose in eight steps (25% overall yield). The synthesis is amenable to multigram scale-up.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Fucose / analogs & derivatives*
  • Fucose / chemical synthesis
  • Galactose / chemistry*
  • Molecular Structure
  • Stereoisomerism

Substances

  • 2-deoxy-L-fucose
  • Fucose
  • Galactose