Abstract
A nonswarming Serratia liquefaciens mutant deficient in serrawettin W2 production was constructed by transposon mutagenesis. Sequence homology indicated that insertion had occurred in gene swrA, which encodes a putative peptide synthetase. Expression of swrA is controlled by quorum sensing.
MeSH terms
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4-Butyrolactone / analogs & derivatives*
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4-Butyrolactone / physiology
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Amino Acid Sequence
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Cell Movement / genetics
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Cell Movement / physiology
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Conserved Sequence
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Extracellular Space / physiology
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Genes, Bacterial
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Lipoproteins / biosynthesis
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Lipoproteins / chemistry
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Lipoproteins / physiology*
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Molecular Sequence Data
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Molecular Structure
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Peptide Synthases / genetics
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Peptide Synthases / physiology
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Peptides, Cyclic / biosynthesis
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Peptides, Cyclic / chemistry
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Peptides, Cyclic / physiology*
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Sequence Homology, Amino Acid
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Serratia / genetics
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Serratia / physiology*
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Surface-Active Agents / chemistry
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Surface-Active Agents / metabolism*
Substances
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Lipoproteins
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N-butyrylhomoserine lactone
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N-hexanoyl-L-homoserine lactone
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Peptides, Cyclic
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Surface-Active Agents
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serrawettin W2
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Peptide Synthases
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4-Butyrolactone