[A case of miliary tuberculosis with brain tuberculoma, following intraocular tuberculosis]

Kekkaku. 1998 Oct;73(10):591-7.
[Article in Japanese]

Abstract

A 52-year-old woman with visual loss of her left eye consulted a ophthalmology clinic. She was conducted left vitrectomy and administered corticosteroid under the diagnosis of uveitis of unknown cause. But her visual acuity was not improved. Although re-surgery was planned, pus retention was found in her left eye. After her left eye was resected, fever and general malaise appeared suddenly. Her chest X-ray film revealed diffuse micronodular opacities. Acid-fast bacilli were detected from her sputum and identified to be Mycobacterium tuberculosis. She was diagnosed miliary tuberculosis, and then antituberculous chemotherapy consisting of 4 drugs was started. Granulomatous inflammation destructing retina and numerous acid-fact bacilli were found in histologic examination of the resected eye. This case was thought to be miliary tuberculosis disseminated from intraocular tuberculosis. After 2 months of therapy, neurologic symptoms which might be caused by brain tuberucloma appeared and deteriorated rapidly. But by adding corticosteroid to antituberculous therapy, symptoms were diminished gradually.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Antitubercular Agents / administration & dosage
  • Betamethasone / administration & dosage
  • Drug Therapy, Combination
  • Female
  • Humans
  • Middle Aged
  • Tuberculoma, Intracranial / drug therapy
  • Tuberculoma, Intracranial / etiology*
  • Tuberculosis, Miliary / drug therapy
  • Tuberculosis, Miliary / etiology*
  • Tuberculosis, Ocular / complications*
  • Tuberculosis, Ocular / drug therapy

Substances

  • Anti-Inflammatory Agents
  • Antitubercular Agents
  • Betamethasone