Intrafamilial association of pericentric inversion of chromosome 9, inv (9)(p11-q21), and rapid cycling bipolar disorder

Psychiatr Genet. 1998 Winter;8(4):259-62. doi: 10.1097/00041444-199808040-00011.

Abstract

Association of a chromosome aberration and psychiatric disorder can be useful in highlighting a genomic region that can be profitably explored further using positional cloning. We report the case of a father and daughter both of whom have bipolar disorder II and a pericentric inversion of chromosome 9.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bipolar Disorder / complications
  • Bipolar Disorder / genetics*
  • Child
  • Chromosome Inversion*
  • Chromosomes, Human, Pair 9 / genetics
  • Chromosomes, Human, Pair 9 / ultrastructure*
  • Depression, Postpartum / etiology
  • Depressive Disorder, Major / genetics
  • Dyslexia
  • Female
  • Humans
  • Intellectual Disability / complications
  • Male
  • Pedigree