Abstract
A convenient solution-phase method for N-alkylation reactions of weakly acidic heterocycles employing polymer supported super base PBEMP is described. By using this method, multiple-step and chemoselective N-alkylation sequences can be carried out in a one-pot process.
MeSH terms
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Alkylation
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Chemistry, Organic / methods
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Heterocyclic Compounds / chemical synthesis*
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Heterocyclic Compounds / chemistry*
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Heterocyclic Compounds, 1-Ring
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Hydrogen-Ion Concentration
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Indicators and Reagents
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Models, Molecular
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Molecular Structure
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Organophosphorus Compounds
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Polymers
Substances
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Heterocyclic Compounds
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Heterocyclic Compounds, 1-Ring
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Indicators and Reagents
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Organophosphorus Compounds
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Polymers
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BEMP phosphazene