Development of primary leiomyosarcoma of the sternum postirradiation: report of a case

Surg Today. 1998;28(12):1326-8. doi: 10.1007/BF02482828.

Abstract

We report herein the case of a 30-year-old man who developed a primary leiomyosarcoma (LMS) 11 years after undergoing a median sternotomy for mediastinal seminoma followed by 50 Gy radiotherapy. He was given two courses of chemotherapy, resulting in 90% tumor regression, after which resection of the tumor with adjacent chest wall structures was carried out. Reconstruction was performed using a methylmethacrylate prosthesis prepared preoperatively. Postoperatively, he received two additional courses of chemotherapy and has had no sign of recurrence for 45 months.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiography
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / pathology
  • Bone Neoplasms / therapy*
  • Humans
  • Leiomyosarcoma / diagnosis
  • Leiomyosarcoma / pathology
  • Leiomyosarcoma / therapy*
  • Male
  • Methylmethacrylates
  • Neoplasms, Radiation-Induced / diagnosis
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Radiation-Induced / therapy*
  • Neoplasms, Second Primary / diagnosis
  • Neoplasms, Second Primary / pathology
  • Neoplasms, Second Primary / therapy*
  • Prostheses and Implants
  • Sternum*
  • Tomography, X-Ray Computed

Substances

  • Methylmethacrylates