Abstract
Four new bisindoles of the vobasine-iboga type, conodiparines A-D were obtained from Tabernaemontana corymbosa which showed appreciable activity in reversing resistance in vincristine-resistant KB cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / pharmacology*
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Drug Resistance, Multiple*
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Drug Resistance, Neoplasm*
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Indoles / chemistry
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Indoles / isolation & purification*
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Indoles / pharmacology
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plants / chemistry*
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Tumor Cells, Cultured
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Vincristine / pharmacology*
Substances
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Antineoplastic Agents, Phytogenic
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Indoles
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Vincristine