Statistics from genitourinary medicine (GUM) clinics provide the most comprehensive source of data on the epidemiology of sexually transmitted infections (STI) in England. Between 1996 and 1997, the total number of diagnoses made in GUM clinics rose by 7% and total diagnoses of acute STIs by 9%. Diagnoses of genital Chlamydia trachomatis, genital warts and gonorrhoea rose by 20%, 8%, and 5%, respectively. Cases of infectious syphilis rose by 26%, most of which was attributable to an outbreak in Bristol. These rises followed substantial rises in acute STIs between 1995 and 1996, and were most pronounced among teenagers and homosexual and bisexual men. The continued growth in numbers of acute STIs is occurring despite the targeting of known risk groups in sexual health education and intervention programmes, and suggests that renewed efforts to improve sexual health are needed.