Orthotopic liver transplantation for hepatitis C infection: the best Christmas present?

Ulster Med J. 1998 Nov;67(2):134-6.

Abstract

We report the case of a 60-year-old man with mild Christmas disease, Factor IX 10% of normal, who developed chronic hepatitis C infection after receiving coagulation factor concentrates. Subsequently he developed encephalopathy and liver failure and was referred for liver transplantation. Following transplantation, Factor IX levels rapidly normalised and have remained so, representing a phenotypic cure of his Christmas disease.

Publication types

  • Case Reports

MeSH terms

  • Blood Coagulation Factors / administration & dosage
  • Factor IX / metabolism
  • Hemophilia B / blood
  • Hemophilia B / complications*
  • Hemophilia B / therapy
  • Hepatitis C, Chronic / blood
  • Hepatitis C, Chronic / complications*
  • Hepatitis C, Chronic / surgery
  • Humans
  • Liver Failure / blood
  • Liver Failure / etiology*
  • Liver Failure / surgery*
  • Liver Transplantation*
  • Male
  • Middle Aged

Substances

  • Blood Coagulation Factors
  • Factor IX