Abstract
The mouse intestinal epithelium undergoes rapid renewal throughout life, thereby requiring continuous coordination of its cellular proliferation, differentiation, and death programs. Recent advances in our understanding of this process have highlighted some of the molecules that regulate renewal and their potential roles in gut neoplasia.
MeSH terms
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Animals
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Cell Division / genetics
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Colorectal Neoplasms / genetics
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Colorectal Neoplasms / pathology
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Epithelial Cells / cytology
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Epithelial Cells / metabolism
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Epithelial Cells / pathology
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Gene Expression Regulation, Neoplastic
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Genes, APC / genetics
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Intestinal Mucosa / cytology*
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Intestinal Mucosa / pathology
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Intestinal Polyps / genetics
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Intestinal Polyps / pathology
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Intestine, Small / cytology*
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Intestine, Small / pathology
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Mice