Cytotoxic isoprenylated flavans of Broussonetia kazinoki

J Nat Prod. 1999 Jan;62(1):164-6. doi: 10.1021/np980281c.

Abstract

Two new prenylflavans [kazinols Q (1) and R (2)] and five known compounds [kazinols D (3), K (4), and H, 7,4'-dihydroxyflavan (5), and oleanolic acid] were isolated from the root bark of Broussonetia kazinoki. The cytotoxic activity of 1-5 was evaluated against several different cell lines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plants / chemistry*
  • Spectrum Analysis
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Flavonoids