Abstract
The present study investigated the level of genetic variation among Schistosoma japonicum populations of different geographical origins from mainland China. Polymerase chain reaction-based methods were employed to determine the sequence for a subunit of the mitochondrial NADH dehydrogenase I gene for populations from Zhejiang, Anhui, Jiangxi, Hunan, Hubei and Sichuan. No variation was detectable in the NADH dehydrogenase I sequence within populations from Zhejiang and Hubei, whereas sequence variation of 0.2% was detected within populations from Anhui, Jiangxi, Hunan and Sichuan. Pairwise comparison of the sequences representing the six different populations revealed genetic differences ranging from 0 to 0.6%.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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China
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DNA, Helminth / analysis*
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DNA, Mitochondrial / analysis*
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Genetic Variation*
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Molecular Sequence Data
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NADH Dehydrogenase / genetics*
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Polymerase Chain Reaction / methods
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Polymorphism, Restriction Fragment Length
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Rabbits
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Schistosoma japonicum / genetics*
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Schistosoma japonicum / growth & development
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Schistosoma japonicum / isolation & purification
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Schistosomiasis japonica / parasitology*
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Sequence Analysis, DNA
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Snails / parasitology
Substances
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DNA, Helminth
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DNA, Mitochondrial
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NADH Dehydrogenase
Associated data
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GENBANK/AF056291
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GENBANK/AF056292
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GENBANK/AF056293
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GENBANK/AF056294
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GENBANK/AF056295
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GENBANK/AF056296