5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor antagonist

J Med Chem. 1999 Jan 28;42(2):202-5. doi: 10.1021/jm980532e.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • Biological Availability
  • Cell Line
  • Humans
  • Rats
  • Receptors, Serotonin / drug effects*
  • Serotonin Antagonists / chemistry
  • Serotonin Antagonists / pharmacokinetics
  • Serotonin Antagonists / pharmacology*
  • Sulfonamides / chemistry
  • Sulfonamides / pharmacokinetics
  • Sulfonamides / pharmacology*
  • Thiophenes / chemistry
  • Thiophenes / pharmacokinetics
  • Thiophenes / pharmacology*

Substances

  • Receptors, Serotonin
  • Serotonin Antagonists
  • Sulfonamides
  • Thiophenes
  • serotonin 6 receptor
  • SB 271046