From July 1997 to February 1998 we performed either minimally invasive or endoscopic saphenous vein harvesting in 55 patients and compared the results with those of 46 patients after conventional saphenous vein harvesting. Minimally invasive and endoscopical vein harvesting can be safely performed after a longer learning curve. Patients after minimally invasive and endoscopical saphenous vein harvesting showed fewer wound healing problems and better cosmetic results than after conventional vein harvesting.