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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. Carroll M, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14845-50. doi: 10.1073/pnas.93.25.14845. Proc Natl Acad Sci U S A. 1996. PMID: 8962143 Free PMC article.
H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor beta gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22).
Schwaller J, Anastasiadou E, Cain D, Kutok J, Wojiski S, Williams IR, LaStarza R, Crescenzi B, Sternberg DW, Andreasson P, Schiavo R, Siena S, Mecucci C, Gilliland DG. Schwaller J, et al. Among authors: gilliland dg. Blood. 2001 Jun 15;97(12):3910-8. doi: 10.1182/blood.v97.12.3910. Blood. 2001. PMID: 11389034 Free article.
275 results