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pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.
Lee RJ, Albanese C, Stenger RJ, Watanabe G, Inghirami G, Haines GK 3rd, Webster M, Muller WJ, Brugge JS, Davis RJ, Pestell RG. Lee RJ, et al. Among authors: inghirami g. J Biol Chem. 1999 Mar 12;274(11):7341-50. doi: 10.1074/jbc.274.11.7341. J Biol Chem. 1999. PMID: 10066798 Free article.
p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, Sun H, Muller WJ, Inghirami G, Lisanti MP, Pestell RG. Hulit J, et al. Among authors: inghirami g. Cancer Res. 2006 Sep 1;66(17):8529-41. doi: 10.1158/0008-5472.CAN-06-0149. Cancer Res. 2006. PMID: 16951165
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors.
Cayrol F, Praditsuktavorn P, Fernando TM, Kwiatkowski N, Marullo R, Calvo-Vidal MN, Phillip J, Pera B, Yang SN, Takpradit K, Roman L, Gaudiano M, Crescenzo R, Ruan J, Inghirami G, Zhang T, Cremaschi G, Gray NS, Cerchietti L. Cayrol F, et al. Among authors: inghirami g. Nat Commun. 2017 Jan 30;8:14290. doi: 10.1038/ncomms14290. Nat Commun. 2017. PMID: 28134252 Free PMC article.
PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis.
Linares JF, Zhang X, Martinez-Ordoñez A, Duran A, Kinoshita H, Kasashima H, Nakanishi N, Nakanishi Y, Carelli R, Cappelli L, Arias E, Yashiro M, Ohira M, Patel S, Inghirami G, Loda M, Cuervo AM, Diaz-Meco MT, Moscat J. Linares JF, et al. Among authors: inghirami g. Mol Cell. 2021 Nov 4;81(21):4509-4526.e10. doi: 10.1016/j.molcel.2021.08.039. Epub 2021 Sep 23. Mol Cell. 2021. PMID: 34560002 Free PMC article.
The Rgr oncogene induces tumorigenesis in transgenic mice.
Jiménez M, Pérez de Castro I, Benet M, García JF, Inghirami G, Pellicer A. Jiménez M, et al. Among authors: inghirami g. Cancer Res. 2004 Sep 1;64(17):6041-9. doi: 10.1158/0008-5472.CAN-03-3389. Cancer Res. 2004. PMID: 15342385
STAT3: a multifaceted oncogene.
Levy DE, Inghirami G. Levy DE, et al. Among authors: inghirami g. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10151-10152. doi: 10.1073/pnas.0604042103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801534 Free PMC article. No abstract available.
333 results