Browne PJ - Search Results

1

Novel inhibitors of carboxypeptidase G2 (CPG2): potential use in antibody-directed enzyme prodrug therapy.

Khan TH, Eno-Amooquaye EA, Searle F, Browne PJ, Osborn HM, Burke PJ. Khan TH, et al. Among authors: browne pj. J Med Chem. 1999 Mar 25;42(6):951-6. doi: 10.1021/jm990004i. J Med Chem. 1999. PMID: 10090777

2

Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy.

Hu L, Yu C, Jiang Y, Han J, Li Z, Browne P, Race PR, Knox RJ, Searle PF, Hyde EI. Hu L, et al. J Med Chem. 2003 Nov 6;46(23):4818-21. doi: 10.1021/jm034133h. J Med Chem. 2003. PMID: 14584930

3

Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.

Jiang Y, Han J, Yu C, Vass SO, Searle PF, Browne P, Knox RJ, Hu L. Jiang Y, et al. J Med Chem. 2006 Jul 13;49(14):4333-43. doi: 10.1021/jm051246n. J Med Chem. 2006. PMID: 16821793

4

Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture.

Li Z, Han J, Jiang Y, Browne P, Knox RJ, Hu L. Li Z, et al. Bioorg Med Chem. 2003 Sep 15;11(19):4171-8. doi: 10.1016/s0968-0896(03)00459-0. Bioorg Med Chem. 2003. PMID: 12951148

5

Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs.

Hu L, Wu X, Han J, Chen L, Vass SO, Browne P, Hall BS, Bot C, Gobalakrishnapillai V, Searle PF, Knox RJ, Wilkinson SR. Hu L, et al. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3986-91. doi: 10.1016/j.bmcl.2011.05.009. Epub 2011 May 7. Bioorg Med Chem Lett. 2011. PMID: 21620697

6

Separated human breast epithelial and myoepithelial cells have different growth factor requirements in vitro but can reconstitute normal breast lobuloalveolar structure.

Gomm JJ, Coope RC, Browne PJ, Coombes RC. Gomm JJ, et al. Among authors: browne pj. J Cell Physiol. 1997 Apr;171(1):11-9. doi: 10.1002/(SICI)1097-4652(199704)171:1<11::AID-JCP2>3.0.CO;2-K. J Cell Physiol. 1997. PMID: 9119887

7

A clinical, histopathological and flow cytometric study of 149 complete moles, 146 partial moles and 107 non-molar hydropic abortions.

Paradinas FJ, Browne P, Fisher RA, Foskett M, Bagshawe KD, Newlands E. Paradinas FJ, et al. Histopathology. 1996 Feb;28(2):101-10. doi: 10.1046/j.1365-2559.1996.247295.x. Histopathology. 1996. PMID: 8834517

8

Isolation of pure populations of epithelial and myoepithelial cells from the normal human mammary gland using immunomagnetic separation with Dynabeads.

Gomm JJ, Browne PJ, Coope RC, Liu QY, Buluwela L, Coombes RC. Gomm JJ, et al. Among authors: browne pj. Anal Biochem. 1995 Mar 20;226(1):91-9. doi: 10.1006/abio.1995.1196. Anal Biochem. 1995. PMID: 7785785

9

Diploid hydatidiform moles with fetal red blood cells in molar villi. 1--Pathology, incidence, and prognosis.

Paradinas FJ, Fisher RA, Browne P, Newlands ES. Paradinas FJ, et al. J Pathol. 1997 Feb;181(2):183-8. doi: 10.1002/(SICI)1096-9896(199702)181:2<183::AID-PATH761>3.0.CO;2-5. J Pathol. 1997. PMID: 9120723

10

A paracrine role for myoepithelial cell-derived FGF2 in the normal human breast.

Gomm JJ, Browne PJ, Coope RC, Bansal GS, Yiangou C, Johnston CL, Mason R, Coombes RC. Gomm JJ, et al. Among authors: browne pj. Exp Cell Res. 1997 Jul 10;234(1):165-73. doi: 10.1006/excr.1997.3593. Exp Cell Res. 1997. PMID: 9223382

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