Zan H - Search Results

1

Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.

Zan H, Cerutti A, Dramitinos P, Schaffer A, Li Z, Casali P. Zan H, et al. J Immunol. 1999 Mar 15;162(6):3437-47. J Immunol. 1999. PMID: 10092799 Free PMC article.

2

CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line.

Cerutti A, Zan H, Schaffer A, Bergsagel L, Harindranath N, Max EE, Casali P. Cerutti A, et al. Among authors: zan h. J Immunol. 1998 Mar 1;160(5):2145-57. J Immunol. 1998. PMID: 9498752 Free PMC article.

3

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

Cerutti A, Schaffer A, Shah S, Zan H, Liou HC, Goodwin RG, Casali P. Cerutti A, et al. Among authors: zan h. Immunity. 1998 Aug;9(2):247-56. doi: 10.1016/s1074-7613(00)80607-x. Immunity. 1998. PMID: 9729045 Free PMC article.

4

CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu-->S gamma, S gamma-->S alpha DNA recombination.

Zan H, Cerutti A, Dramitinos P, Schaffer A, Casali P. Zan H, et al. J Immunol. 1998 Nov 15;161(10):5217-25. J Immunol. 1998. PMID: 9820493 Free PMC article.

5

The evolutionarily conserved sequence upstream of the human Ig heavy chain S gamma 3 region is an inducible promoter: synergistic activation by CD40 ligand and IL-4 via cooperative NF-kappa B and STAT-6 binding sites.

Schaffer A, Cerutti A, Shah S, Zan H, Casali P. Schaffer A, et al. Among authors: zan h. J Immunol. 1999 May 1;162(9):5327-36. J Immunol. 1999. PMID: 10228008

6

Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells.

Cerutti A, Schaffer A, Goodwin RG, Shah S, Zan H, Ely S, Casali P. Cerutti A, et al. Among authors: zan h. J Immunol. 2000 Jul 15;165(2):786-94. doi: 10.4049/jimmunol.165.2.786. J Immunol. 2000. PMID: 10878352 Free PMC article.

7

B cell receptor engagement and T cell contact induce Bcl-6 somatic hypermutation in human B cells: identity with Ig hypermutation.

Zan H, Li Z, Yamaji K, Dramitinos P, Cerutti A, Casali P. Zan H, et al. J Immunol. 2000 Jul 15;165(2):830-9. doi: 10.4049/jimmunol.165.2.830. J Immunol. 2000. PMID: 10878357

8

Ongoing hypermutation in the Ig V(D)J gene segments and c-myc proto-oncogene of an AIDS lymphoma segregates with neoplastic B cells at different sites: implications for clonal evolution.

Ikematsu H, Cerutti A, Zan H, Knowles DM, Ikematsu W, Casali P. Ikematsu H, et al. Among authors: zan h. Hum Immunol. 2000 Dec;61(12):1242-53. doi: 10.1016/s0198-8859(00)00181-6. Hum Immunol. 2000. PMID: 11163079 Free article.

9

Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.

Cerutti A, Kim EC, Shah S, Schattner EJ, Zan H, Schaffer A, Casali P. Cerutti A, et al. Among authors: zan h. Nat Immunol. 2001 Feb;2(2):150-6. doi: 10.1038/84254. Nat Immunol. 2001. PMID: 11175813 Free PMC article.

10

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

Zan H, Komori A, Li Z, Cerutti A, Schaffer A, Flajnik MF, Diaz M, Casali P. Zan H, et al. Immunity. 2001 May;14(5):643-53. doi: 10.1016/s1074-7613(01)00142-x. Immunity. 2001. PMID: 11371365 Free PMC article.

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