Huls GA - Search Results

1

A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments.

Huls GA, Heijnen IA, Cuomo ME, Koningsberger JC, Wiegman L, Boel E, van der Vuurst de Vries AR, Loyson SA, Helfrich W, van Berge Henegouwen GP, van Meijer M, de Kruif J, Logtenberg T. Huls GA, et al. Nat Biotechnol. 1999 Mar;17(3):276-81. doi: 10.1038/7023. Nat Biotechnol. 1999. PMID: 10096296

2

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

Roose J, Huls G, van Beest M, Moerer P, van der Horn K, Goldschmeding R, Logtenberg T, Clevers H. Roose J, et al. Science. 1999 Sep 17;285(5435):1923-6. doi: 10.1126/science.285.5435.1923. Science. 1999. PMID: 10489374

3

Antitumor immune effector mechanisms recruited by phage display-derived fully human IgG1 and IgA1 monoclonal antibodies.

Huls G, Heijnen IA, Cuomo E, van der Linden J, Boel E, van de Winkel JG, Logtenberg T. Huls G, et al. Cancer Res. 1999 Nov 15;59(22):5778-84. Cancer Res. 1999. PMID: 10582699

4

Tumor cell killing by in vitro affinity-matured recombinant human monoclonal antibodies.

Huls G, Gestel D, van der Linden J, Moret E, Logtenberg T. Huls G, et al. Cancer Immunol Immunother. 2001 May;50(3):163-71. doi: 10.1007/s002620100182. Cancer Immunol Immunother. 2001. PMID: 11419184 Free PMC article.

5

A novel AML-selective TRAIL fusion protein that is superior to Gemtuzumab Ozogamicin in terms of in vitro selectivity, activity and stability.

ten Cate B, Bremer E, de Bruyn M, Bijma T, Samplonius D, Schwemmlein M, Huls G, Fey G, Helfrich W. ten Cate B, et al. Leukemia. 2009 Aug;23(8):1389-97. doi: 10.1038/leu.2009.34. Epub 2009 Mar 5. Leukemia. 2009. PMID: 19262596

6

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.

Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H. Korinek V, et al. Nat Genet. 1998 Aug;19(4):379-83. doi: 10.1038/1270. Nat Genet. 1998. PMID: 9697701

7

Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.

Barker N, Huls G, Korinek V, Clevers H. Barker N, et al. Am J Pathol. 1999 Jan;154(1):29-35. doi: 10.1016/S0002-9440(10)65247-9. Am J Pathol. 1999. PMID: 9916915 Free PMC article.

8

Enhancement of polymorphonuclear cell-mediated tumor cell killing on simultaneous engagement of fcgammaRI (CD64) and fcalphaRI (CD89).

van Egmond M, van Spriel AB, Vermeulen H, Huls G, van Garderen E, van de Winkel JG. van Egmond M, et al. Cancer Res. 2001 May 15;61(10):4055-60. Cancer Res. 2001. PMID: 11358825

9

A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.

de Graaf M, Boven E, Oosterhoff D, van der Meulen-Muileman IH, Huls GA, Gerritsen WR, Haisma HJ, Pinedo HM. de Graaf M, et al. Among authors: huls ga. Br J Cancer. 2002 Mar 4;86(5):811-8. doi: 10.1038/sj.bjc.6600143. Br J Cancer. 2002. PMID: 11875747 Free PMC article.

10

CD20-selective inhibition of CD47-SIRPα "don't eat me" signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab.

van Bommel PE, He Y, Schepel I, Hendriks MAJM, Wiersma VR, van Ginkel RJ, van Meerten T, Ammatuna E, Huls G, Samplonius DF, Helfrich W, Bremer E. van Bommel PE, et al. Oncoimmunology. 2017 Oct 31;7(2):e1386361. doi: 10.1080/2162402X.2017.1386361. eCollection 2018. Oncoimmunology. 2017. PMID: 29308308 Free PMC article.

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