Jakobovits A - Search Results

1

Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy.

Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG, Jakobovits A. Yang XD, et al. Among authors: jakobovits a. Cancer Res. 1999 Mar 15;59(6):1236-43. Cancer Res. 1999. PMID: 10096554

2

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice.

Mendez MJ, Green LL, Corvalan JR, Jia XC, Maynard-Currie CE, Yang XD, Gallo ML, Louie DM, Lee DV, Erickson KL, Luna J, Roy CM, Abderrahim H, Kirschenbaum F, Noguchi M, Smith DH, Fukushima A, Hales JF, Klapholz S, Finer MH, Davis CG, Zsebo KM, Jakobovits A. Mendez MJ, et al. Among authors: jakobovits a. Nat Genet. 1997 Feb;15(2):146-56. doi: 10.1038/ng0297-146. Nat Genet. 1997. PMID: 9020839

3

The human immunoglobulin loci introduced into mice: V (D) and J gene segment usage similar to that of adult humans.

Gallo ML, Ivanov VE, Jakobovits A, Davis CG. Gallo ML, et al. Among authors: jakobovits a. Eur J Immunol. 2000 Feb;30(2):534-40. doi: 10.1002/1521-4141(200002)30:2<534::AID-IMMU534>3.0.CO;2-P. Eur J Immunol. 2000. PMID: 10671209 Free article.

4

Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo.

Challita-Eid PM, Morrison K, Etessami S, An Z, Morrison KJ, Perez-Villar JJ, Raitano AB, Jia XC, Gudas JM, Kanner SB, Jakobovits A. Challita-Eid PM, et al. Among authors: jakobovits a. Cancer Res. 2007 Jun 15;67(12):5798-805. doi: 10.1158/0008-5472.CAN-06-3849. Cancer Res. 2007. PMID: 17575147

5

From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice.

Jakobovits A, Amado RG, Yang X, Roskos L, Schwab G. Jakobovits A, et al. Nat Biotechnol. 2007 Oct;25(10):1134-43. doi: 10.1038/nbt1337. Nat Biotechnol. 2007. PMID: 17921999

6

Production and selection of antigen-specific fully human monoclonal antibodies from mice engineered with human Ig loci.

Jakobovits A. Jakobovits A. Adv Drug Deliv Rev. 1998 Apr 6;31(1-2):33-42. doi: 10.1016/s0169-409x(97)00092-6. Adv Drug Deliv Rev. 1998. PMID: 10837616

7

Monoclonal antibody therapy for prostate cancer.

Jakobovits A. Jakobovits A. Handb Exp Pharmacol. 2008;(181):237-56. doi: 10.1007/978-3-540-73259-4_11. Handb Exp Pharmacol. 2008. PMID: 18071949 Review.

8

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

Afar DE, Vivanco I, Hubert RS, Kuo J, Chen E, Saffran DC, Raitano AB, Jakobovits A. Afar DE, et al. Among authors: jakobovits a. Cancer Res. 2001 Feb 15;61(4):1686-92. Cancer Res. 2001. PMID: 11245484

9

Production of fully human antibodies by transgenic mice.

Jakobovits A. Jakobovits A. Curr Opin Biotechnol. 1995 Oct;6(5):561-6. doi: 10.1016/0958-1669(95)80093-x. Curr Opin Biotechnol. 1995. PMID: 7579668 Review.

10

The long-awaited magic bullets: therapeutic human monoclonal antibodies from transgenic mice.

Jakobovits A. Jakobovits A. Expert Opin Investig Drugs. 1998 Apr;7(4):607-14. doi: 10.1517/13543784.7.4.607. Expert Opin Investig Drugs. 1998. PMID: 15991997

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