Tam RC - Search Results

1

Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile.

Tam RC, Pai B, Bard J, Lim C, Averett DR, Phan UT, Milovanovic T. Tam RC, et al. J Hepatol. 1999 Mar;30(3):376-82. doi: 10.1016/s0168-8278(99)80093-2. J Hepatol. 1999. PMID: 10190717

2

Oligonucleotide-mediated inhibition of CD28 expression induces human T cell hyporesponsiveness and manifests impaired contact hypersensitivity in mice.

Tam RC, Phan UT, Milovanovic T, Pai B, Lim C, Bard J, He L. Tam RC, et al. J Immunol. 1997 Jan 1;158(1):200-8. J Immunol. 1997. PMID: 8977191

3

Contact hypersensitivity responses following ribavirin treatment in vivo are influenced by type 1 cytokine polarization, regulation of IL-10 expression, and costimulatory signaling.

Tam RC, Lim C, Bard J, Pai B. Tam RC, et al. J Immunol. 1999 Oct 1;163(7):3709-17. J Immunol. 1999. PMID: 10490966

4

Monocyclic L-nucleosides with type 1 cytokine-inducing activity.

Ramasamy KS, Tam RC, Bard J, Averett DR. Ramasamy KS, et al. Among authors: tam rc. J Med Chem. 2000 Mar 9;43(5):1019-28. doi: 10.1021/jm9905514. J Med Chem. 2000. PMID: 10715165

5

The ribavirin analog ICN 17261 demonstrates reduced toxicity and antiviral effects with retention of both immunomodulatory activity and reduction of hepatitis-induced serum alanine aminotransferase levels.

Tam RC, Ramasamy K, Bard J, Pai B, Lim C, Averett DR. Tam RC, et al. Antimicrob Agents Chemother. 2000 May;44(5):1276-83. doi: 10.1128/AAC.44.5.1276-1283.2000. Antimicrob Agents Chemother. 2000. PMID: 10770762 Free PMC article.

6

Increased potency of an aptameric G-rich oligonucleotide is associated with novel functional properties of phosphorothioate linkages.

Tam RC, Wu-Pong S, Pai B, Lim C, Chan A, Thomas DF, Milovanovic T, Bard J, Middleton PJ. Tam RC, et al. Antisense Nucleic Acid Drug Dev. 1999 Jun;9(3):289-300. doi: 10.1089/oli.1.1999.9.289. Antisense Nucleic Acid Drug Dev. 1999. PMID: 10435754

7

Synthesis and cytokine modulation properties of pyrrolo[2, 3-d]-4-pyrimidone nucleosides.

Wang G, Tam RC, Gunic E, Du J, Bard J, Pai B. Wang G, et al. Among authors: tam rc. J Med Chem. 2000 Jun 29;43(13):2566-74. doi: 10.1021/jm000035+. J Med Chem. 2000. PMID: 10891116

8

Inhibition of CD28 expression by oligonucleotide decoys to the regulatory element in exon 1 of the CD28 gene.

Tam RC, Lin CJ, Lim C, Pai B, Stoisavljevic V. Tam RC, et al. J Immunol. 1999 Oct 15;163(8):4292-9. J Immunol. 1999. PMID: 10510368

9

Comparative analysis of anti-hepatitis C virus activity and gene expression mediated by alpha, beta, and gamma interferons.

Cheney IW, Lai VC, Zhong W, Brodhag T, Dempsey S, Lim C, Hong Z, Lau JY, Tam RC. Cheney IW, et al. Among authors: tam rc. J Virol. 2002 Nov;76(21):11148-54. doi: 10.1128/jvi.76.21.11148-11154.2002. J Virol. 2002. PMID: 12368359 Free PMC article.

10

Mechanism of action of ribavirin in the combination treatment of chronic HCV infection.

Lau JY, Tam RC, Liang TJ, Hong Z. Lau JY, et al. Among authors: tam rc. Hepatology. 2002 May;35(5):1002-9. doi: 10.1053/jhep.2002.32672. Hepatology. 2002. PMID: 11981750 Review. No abstract available.

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