Ladbury JE - Search Results

1

Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate.

Baraldi E, Djinovic Carugo K, Hyvönen M, Surdo PL, Riley AM, Potter BV, O'Brien R, Ladbury JE, Saraste M. Baraldi E, et al. Among authors: ladbury je. Structure. 1999 Apr 15;7(4):449-60. doi: 10.1016/s0969-2126(99)80057-4. Structure. 1999. PMID: 10196129 Free article.

2

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin.

Tsai FT, Singh OM, Skarzynski T, Wonacott AJ, Weston S, Tucker A, Pauptit RA, Breeze AL, Poyser JP, O'Brien R, Ladbury JE, Wigley DB. Tsai FT, et al. Among authors: ladbury je. Proteins. 1997 May;28(1):41-52. Proteins. 1997. PMID: 9144789

3

The adaptability of Escherichia coli thioredoxin to non-conservative amino acid substitutions.

O'Brien R, Wynn R, Driscoll PC, Davis B, Plaxco KW, Sturtevant JM, Ladbury JE. O'Brien R, et al. Among authors: ladbury je. Protein Sci. 1997 Jun;6(6):1325-32. doi: 10.1002/pro.5560060621. Protein Sci. 1997. PMID: 9194193 Free PMC article.

4

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone.

Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Prodromou C, et al. Among authors: ladbury je. Cell. 1997 Jul 11;90(1):65-75. doi: 10.1016/s0092-8674(00)80314-1. Cell. 1997. PMID: 9230303 Free article.

5

The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon.

O'Brien R, DeDecker B, Fleming KG, Sigler PB, Ladbury JE. O'Brien R, et al. Among authors: ladbury je. J Mol Biol. 1998 May 29;279(1):117-25. doi: 10.1006/jmbi.1998.1743. J Mol Biol. 1998. PMID: 9636704 Free article.

6

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo.

Panaretou B, Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Panaretou B, et al. Among authors: ladbury je. EMBO J. 1998 Aug 17;17(16):4829-36. doi: 10.1093/emboj/17.16.4829. EMBO J. 1998. PMID: 9707442 Free PMC article.

7

Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides.

Chung E, Henriques D, Renzoni D, Zvelebil M, Bradshaw JM, Waksman G, Robinson CV, Ladbury JE. Chung E, et al. Among authors: ladbury je. Structure. 1998 Sep 15;6(9):1141-51. doi: 10.1016/s0969-2126(98)00115-4. Structure. 1998. PMID: 9753693 Free article.

8

RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.

Arold S, O'Brien R, Franken P, Strub MP, Hoh F, Dumas C, Ladbury JE. Arold S, et al. Among authors: ladbury je. Biochemistry. 1998 Oct 20;37(42):14683-91. doi: 10.1021/bi980989q. Biochemistry. 1998. PMID: 9778343

9

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin.

Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Roe SM, et al. Among authors: ladbury je. J Med Chem. 1999 Jan 28;42(2):260-6. doi: 10.1021/jm980403y. J Med Chem. 1999. PMID: 9925731

10

Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones.

Prodromou C, Siligardi G, O'Brien R, Woolfson DN, Regan L, Panaretou B, Ladbury JE, Piper PW, Pearl LH. Prodromou C, et al. Among authors: ladbury je. EMBO J. 1999 Feb 1;18(3):754-62. doi: 10.1093/emboj/18.3.754. EMBO J. 1999. PMID: 9927435 Free PMC article.

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