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Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors.
J Med Chem. 1999 May 6;42(9):1525-36. doi: 10.1021/jm9803222.
J Med Chem. 1999.
PMID: 10229623
Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-alpha receptors in a human colon adenocarcinoma (Colo 205) cell line.
Lombard MA, Wallace TL, Kubicek MF, Petzold GL, Mitchell MA, Hendges SK, Wilks JW.
Lombard MA, et al. Among authors: hendges sk.
Cancer Res. 1998 Sep 1;58(17):4001-7.
Cancer Res. 1998.
PMID: 9731514
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Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.
Brickner SJ, Hutchinson DK, Barbachyn MR, Manninen PR, Ulanowicz DA, Garmon SA, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE.
Brickner SJ, et al. Among authors: hendges sk.
J Med Chem. 1996 Feb 2;39(3):673-9. doi: 10.1021/jm9509556.
J Med Chem. 1996.
PMID: 8576909
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Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity.
Barbachyn MR, Hutchinson DK, Brickner SJ, Cynamon MH, Kilburn JO, Klemens SP, Glickman SE, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE.
Barbachyn MR, et al. Among authors: hendges sk.
J Med Chem. 1996 Feb 2;39(3):680-5. doi: 10.1021/jm950956y.
J Med Chem. 1996.
PMID: 8576910
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