Urwyler S - Search Results

1

(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.

Gasparini F, Bruno V, Battaglia G, Lukic S, Leonhardt T, Inderbitzin W, Laurie D, Sommer B, Varney MA, Hess SD, Johnson EC, Kuhn R, Urwyler S, Sauer D, Portet C, Schmutz M, Nicoletti F, Flor PJ. Gasparini F, et al. Among authors: urwyler s. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. J Pharmacol Exp Ther. 1999. PMID: 10336568

2

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.

Gasparini F, Lingenhöhl K, Stoehr N, Flor PJ, Heinrich M, Vranesic I, Biollaz M, Allgeier H, Heckendorn R, Urwyler S, Varney MA, Johnson EC, Hess SD, Rao SP, Sacaan AI, Santori EM, Veliçelebi G, Kuhn R. Gasparini F, et al. Among authors: urwyler s. Neuropharmacology. 1999 Oct;38(10):1493-503. doi: 10.1016/s0028-3908(99)00082-9. Neuropharmacology. 1999. PMID: 10530811

3

Biphenyl-derivatives of 2-amino-7-phosphonoheptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonist--I. Pharmacological characterization in vitro.

Urwyler S, Laurie D, Lowe DA, Meier CL, Müller W. Urwyler S, et al. Neuropharmacology. 1996 Jun;35(6):643-54. doi: 10.1016/0028-3908(96)84636-3. Neuropharmacology. 1996. PMID: 8887974

4

Design, synthesis and preliminary evaluation of novel 3'-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors.

Pellicciari R, Costantino G, Marinozzi M, Macchiarulo A, Amori L, Josef Flor P, Gasparini F, Kuhn R, Urwyler S. Pellicciari R, et al. Among authors: urwyler s. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3179-82. doi: 10.1016/s0960-894x(01)00656-4. Bioorg Med Chem Lett. 2001. PMID: 11720869

5

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

Urwyler S, Pozza MF, Lingenhoehl K, Mosbacher J, Lampert C, Froestl W, Koller M, Kaupmann K. Urwyler S, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):322-30. doi: 10.1124/jpet.103.053074. Epub 2003 Sep 3. J Pharmacol Exp Ther. 2003. PMID: 12954816

6

ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.

Hintermann S, Vranesic I, Allgeier H, Brülisauer A, Hoyer D, Lemaire M, Moenius T, Urwyler S, Whitebread S, Gasparini F, Auberson YP. Hintermann S, et al. Among authors: urwyler s. Bioorg Med Chem. 2007 Jan 15;15(2):903-14. doi: 10.1016/j.bmc.2006.10.038. Epub 2006 Oct 21. Bioorg Med Chem. 2007. PMID: 17110115

7

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.

Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K. Urwyler S, et al. Mol Pharmacol. 2001 Nov;60(5):963-71. Mol Pharmacol. 2001. PMID: 11641424

8

Quinazolinedione sulfonamides: a novel class of competitive AMPA receptor antagonists with oral activity.

Koller M, Lingenhoehl K, Schmutz M, Vranesic IT, Kallen J, Auberson YP, Carcache DA, Mattes H, Ofner S, Orain D, Urwyler S. Koller M, et al. Among authors: urwyler s. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3358-61. doi: 10.1016/j.bmcl.2011.04.017. Epub 2011 Apr 8. Bioorg Med Chem Lett. 2011. PMID: 21531559

9

Inorganic iron complexes derived from the nitric oxide donor nitroprusside: competitive N-methyl-D-aspartate receptor antagonists with nanomolar affinity.

Neijt H, Koller M, Urwyler S. Neijt H, et al. Among authors: urwyler s. Biochem Pharmacol. 2001 Feb 1;61(3):343-9. doi: 10.1016/s0006-2952(00)00566-9. Biochem Pharmacol. 2001. PMID: 11172739

10

Changes in the properties of allosteric and orthosteric GABAB receptor ligands after a continuous, desensitizing agonist pretreatment.

Gjoni T, Urwyler S. Gjoni T, et al. Among authors: urwyler s. Eur J Pharmacol. 2009 Jan 28;603(1-3):37-41. doi: 10.1016/j.ejphar.2008.12.014. Epub 2008 Dec 16. Eur J Pharmacol. 2009. PMID: 19109945

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