Bostwick JS - Search Results

1

RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit.

Bostwick JS, Bentley R, Morgan S, Brown K, Chu V, Ewing WR, Spada AP, Pauls H, Perrone MH, Dunwiddie CT, Leadley RJ Jr. Bostwick JS, et al. Thromb Haemost. 1999 Jan;81(1):157-60. Thromb Haemost. 1999. PMID: 10348709

2

Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.

Ewing WR, Becker MR, Manetta VE, Davis RS, Pauls HW, Mason H, Choi-Sledeski YM, Green D, Cha D, Spada AP, Cheney DL, Mason JS, Maignan S, Guilloteau JP, Brown K, Colussi D, Bentley R, Bostwick J, Kasiewski CJ, Morgan SR, Leadley RJ, Dunwiddie CT, Perrone MH, Chu V. Ewing WR, et al. Among authors: bostwick j. J Med Chem. 1999 Sep 9;42(18):3557-71. doi: 10.1021/jm990040h. J Med Chem. 1999. PMID: 10479288

3

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors.

Becker MR, Ewing WR, Davis RS, Pauls HW, Ly C, Li A, Mason HJ, Choi-Sledeski YM, Spada AP, Chu V, Brown KD, Colussi DJ, Leadley RJ, Bentley R, Bostwick J, Kasiewski C, Morgan S. Becker MR, et al. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2753-8. doi: 10.1016/s0960-894x(99)00466-7. Bioorg Med Chem Lett. 1999. PMID: 10509929

4

Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis.

Heran C, Morgan S, Kasiewski C, Bostwick J, Bentley R, Klein S, Chu V, Brown K, Colussi D, Czekaj M, Perrone M, Leadley R Jr. Heran C, et al. Eur J Pharmacol. 2000 Feb 18;389(2-3):201-7. doi: 10.1016/s0014-2999(99)00902-4. Eur J Pharmacol. 2000. PMID: 10688985

5

Pharmacological characterization of a novel factor Xa inhibitor, FXV673.

Chu V, Brown K, Colussi D, Gao J, Bostwick J, Kasiewski C, Bentley R, Morgan S, Guertin K, Pauls HW, Gong Y, Zulli A, Perrone MH, Dunwiddie CT, Leadley RJ. Chu V, et al. Thromb Res. 2001 Aug 15;103(4):309-24. doi: 10.1016/s0049-3848(01)00328-0. Thromb Res. 2001. PMID: 11562341

6

Anti-thrombotic activity of RG13965, a novel platelet fibrinogen receptor antagonist.

Bostwick JS, Kasiewski CJ, Chu V, Klein SI, Sabatino RD, Perrone MH, Dunwiddie CT, Cook JJ, Leadley RJ Jr. Bostwick JS, et al. Thromb Res. 1996 Jun 15;82(6):495-507. doi: 10.1016/0049-3848(96)00100-4. Thromb Res. 1996. PMID: 8794522

7

Comparison of enoxaparin, hirulog, and heparin as adjunctive antithrombotic therapy during thrombolysis with rtPA in the stenosed canine coronary artery.

Leadley RJ Jr, Kasiewski CJ, Bostwick JS, Bentley R, McVey MJ, White FJ, Perrone MH, Dunwiddie CT. Leadley RJ Jr, et al. Among authors: bostwick js. Thromb Haemost. 1997 Oct;78(4):1278-85. Thromb Haemost. 1997. PMID: 9364998

8

Inhibition of repetitive thrombus formation in the stenosed canine coronary artery by enoxaparin, but not by unfractionated heparin.

Leadley RJ Jr, Kasiewski CJ, Bostwick JS, Bentley R, Dunwiddie CT, Perrone MH. Leadley RJ Jr, et al. Among authors: bostwick js. Arterioscler Thromb Vasc Biol. 1998 Jun;18(6):908-14. doi: 10.1161/01.atv.18.6.908. Arterioscler Thromb Vasc Biol. 1998. PMID: 9633930

9

Pharmacodynamic activity and antithrombotic efficacy of RPR120844, a novel inhibitor of coagulation factor Xa.

Leadley RJ Jr, Morgan SR, Bentley R, Bostwick JS, Kasiewski CJ, Heran C, Chu V, Brown K, Moxey P, Ewing WR, Pauls H, Spada AP, Perrone MH, Dunwiddie CT. Leadley RJ Jr, et al. Among authors: bostwick js. J Cardiovasc Pharmacol. 1999 Dec;34(6):791-9. doi: 10.1097/00005344-199912000-00004. J Cardiovasc Pharmacol. 1999. PMID: 10598121

10

Superiority of enoxaparin over heparin in combination with a GPIIb/IIIa receptor antagonist during coronary thrombolysis in dogs.

Rebello SS, Kasiewski CJ, Bentley RG, Morgan SR, Chu V, Bostwick JS, Klein SI, Perrone MH, Leadley RJ. Rebello SS, et al. Among authors: bostwick js. Thromb Res. 2001 May 1;102(3):261-71. doi: 10.1016/s0049-3848(01)00242-0. Thromb Res. 2001. PMID: 11369420

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