Chu V - Search Results

1

RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit.

Bostwick JS, Bentley R, Morgan S, Brown K, Chu V, Ewing WR, Spada AP, Pauls H, Perrone MH, Dunwiddie CT, Leadley RJ Jr. Bostwick JS, et al. Among authors: chu v. Thromb Haemost. 1999 Jan;81(1):157-60. Thromb Haemost. 1999. PMID: 10348709

2

Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.

Ewing WR, Becker MR, Manetta VE, Davis RS, Pauls HW, Mason H, Choi-Sledeski YM, Green D, Cha D, Spada AP, Cheney DL, Mason JS, Maignan S, Guilloteau JP, Brown K, Colussi D, Bentley R, Bostwick J, Kasiewski CJ, Morgan SR, Leadley RJ, Dunwiddie CT, Perrone MH, Chu V. Ewing WR, et al. Among authors: chu v. J Med Chem. 1999 Sep 9;42(18):3557-71. doi: 10.1021/jm990040h. J Med Chem. 1999. PMID: 10479288

3

Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.

Choi-Sledeski YM, McGarry DG, Green DM, Mason HJ, Becker MR, Davis RS, Ewing WR, Dankulich WP, Manetta VE, Morris RL, Spada AP, Cheney DL, Brown KD, Colussi DJ, Chu V, Heran CL, Morgan SR, Bentley RG, Leadley RJ, Maignan S, Guilloteau JP, Dunwiddie CT, Pauls HW. Choi-Sledeski YM, et al. Among authors: chu v. J Med Chem. 1999 Sep 9;42(18):3572-87. doi: 10.1021/jm990041+. J Med Chem. 1999. PMID: 10479289

4

Aminoisoquinolines: design and synthesis of an orally active benzamidine isostere for the inhibition of factor XA.

Choi-Sledeski YM, Becker MR, Green DM, Davis R, Ewing WR, Mason HJ, Ly C, Spada A, Liang G, Cheney D, Barton J, Chu V, Brown K, Colussi D, Bentley R, Leadley R, Dunwiddie C, Pauls HW. Choi-Sledeski YM, et al. Among authors: chu v. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2539-44. doi: 10.1016/s0960-894x(99)00421-7. Bioorg Med Chem Lett. 1999. PMID: 10498204

5

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors.

Becker MR, Ewing WR, Davis RS, Pauls HW, Ly C, Li A, Mason HJ, Choi-Sledeski YM, Spada AP, Chu V, Brown KD, Colussi DJ, Leadley RJ, Bentley R, Bostwick J, Kasiewski C, Morgan S. Becker MR, et al. Among authors: chu v. Bioorg Med Chem Lett. 1999 Sep 20;9(18):2753-8. doi: 10.1016/s0960-894x(99)00466-7. Bioorg Med Chem Lett. 1999. PMID: 10509929

6

Pharmacodynamic activity and antithrombotic efficacy of RPR120844, a novel inhibitor of coagulation factor Xa.

Leadley RJ Jr, Morgan SR, Bentley R, Bostwick JS, Kasiewski CJ, Heran C, Chu V, Brown K, Moxey P, Ewing WR, Pauls H, Spada AP, Perrone MH, Dunwiddie CT. Leadley RJ Jr, et al. Among authors: chu v. J Cardiovasc Pharmacol. 1999 Dec;34(6):791-9. doi: 10.1097/00005344-199912000-00004. J Cardiovasc Pharmacol. 1999. PMID: 10598121

7

Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis.

Heran C, Morgan S, Kasiewski C, Bostwick J, Bentley R, Klein S, Chu V, Brown K, Colussi D, Czekaj M, Perrone M, Leadley R Jr. Heran C, et al. Among authors: chu v. Eur J Pharmacol. 2000 Feb 18;389(2-3):201-7. doi: 10.1016/s0014-2999(99)00902-4. Eur J Pharmacol. 2000. PMID: 10688985

8

Amido-(propyl and allyl)-hydroxybenzamidines: development of achiral inhibitors of factor Xa.

Gong Y, Pauls HW, Spada AP, Czekaj M, Liang G, Chu V, Colussi DJ, Brown KD, Gao J. Gong Y, et al. Among authors: chu v. Bioorg Med Chem Lett. 2000 Feb 7;10(3):217-21. doi: 10.1016/s0960-894x(99)00673-3. Bioorg Med Chem Lett. 2000. PMID: 10698439

9

In vitro characterization of a novel factor Xa inhibitor, RPR 130737.

Chu V, Brown K, Colussi D, Choi YM, Green D, Pauls HW, Spada AP, Perrone MH, Leadley RJ Jr, Dunwiddie CT. Chu V, et al. Thromb Res. 2000 Jul 1;99(1):71-82. doi: 10.1016/s0049-3848(00)00227-9. Thromb Res. 2000. PMID: 11012377

10

Superiority of enoxaparin over heparin in combination with a GPIIb/IIIa receptor antagonist during coronary thrombolysis in dogs.

Rebello SS, Kasiewski CJ, Bentley RG, Morgan SR, Chu V, Bostwick JS, Klein SI, Perrone MH, Leadley RJ. Rebello SS, et al. Among authors: chu v. Thromb Res. 2001 May 1;102(3):261-71. doi: 10.1016/s0049-3848(01)00242-0. Thromb Res. 2001. PMID: 11369420

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