Jarvis MF - Search Results

1

Site and event specific increase of striatal adenosine release by adenosine kinase inhibition in rats.

Britton DR, Mikusa J, Lee CH, Jarvis MF, Williams M, Kowaluk EA. Britton DR, et al. Among authors: jarvis mf. Neurosci Lett. 1999 May 7;266(2):93-6. doi: 10.1016/s0304-3940(99)00280-3. Neurosci Lett. 1999. PMID: 10353335

2

Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats.

Jarvis MF, Mikusa J, Chu KL, Wismer CT, Honore P, Kowaluk EA, McGaraughty S. Jarvis MF, et al. Pharmacol Biochem Behav. 2002 Oct;73(3):573-81. doi: 10.1016/s0091-3057(02)00840-7. Pharmacol Biochem Behav. 2002. PMID: 12151032

3

Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors.

Gomtsyan A, Didomenico S, Lee CH, Matulenko MA, Kim K, Kowaluk EA, Wismer CT, Mikusa J, Yu H, Kohlhaas K, Jarvis MF, Bhagwat SS. Gomtsyan A, et al. Among authors: jarvis mf. J Med Chem. 2002 Aug 15;45(17):3639-48. doi: 10.1021/jm020049a. J Med Chem. 2002. PMID: 12166937

4

Synthesis and biological evaluation of pteridine and pyrazolopyrimidine based adenosine kinase inhibitors.

Gomtsyan A, Didomenico S, Lee CH, Stewart AO, Bhagwat SS, Kowaluk EA, Jarvis MF. Gomtsyan A, et al. Among authors: jarvis mf. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4165-8. doi: 10.1016/j.bmcl.2004.06.029. Bioorg Med Chem Lett. 2004. PMID: 15261263

5

Therapeutic potential of adenosine kinase inhibitors.

Kowaluk EA, Jarvis MF. Kowaluk EA, et al. Among authors: jarvis mf. Expert Opin Investig Drugs. 2000 Mar;9(3):551-64. doi: 10.1517/13543784.9.3.551. Expert Opin Investig Drugs. 2000. PMID: 11060695 Review.

6

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.

Jarvis MF, Yu H, Kohlhaas K, Alexander K, Lee CH, Jiang M, Bhagwat SS, Williams M, Kowaluk EA. Jarvis MF, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):1156-64. J Pharmacol Exp Ther. 2000. PMID: 11082453

7

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat.

Kowaluk EA, Mikusa J, Wismer CT, Zhu CZ, Schweitzer E, Lynch JJ, Lee CH, Jiang M, Bhagwat SS, Gomtsyan A, McKie J, Cox BF, Polakowski J, Reinhart G, Williams M, Jarvis MF. Kowaluk EA, et al. Among authors: jarvis mf. J Pharmacol Exp Ther. 2000 Dec;295(3):1165-74. J Pharmacol Exp Ther. 2000. PMID: 11082454

8

Structure-activity studies of 5-substituted pyridopyrimidines as adenosine kinase inhibitors.

Cowart M, Lee CH, Gfesser GA, Bayburt EK, Bhagwat SS, Stewart AO, Yu H, Kohlhaas KL, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Alexander KM, Jarvis MF, Kowaluk EA. Cowart M, et al. Among authors: jarvis mf. Bioorg Med Chem Lett. 2001 Jan 8;11(1):83-6. doi: 10.1016/s0960-894x(00)00602-8. Bioorg Med Chem Lett. 2001. PMID: 11140740

9

Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: evaluation of the sites of action.

McGaraughty S, Chu KL, Wismer CT, Mikusa J, Zhu CZ, Cowart M, Kowaluk EA, Jarvis MF. McGaraughty S, et al. Among authors: jarvis mf. J Pharmacol Exp Ther. 2001 Feb;296(2):501-9. J Pharmacol Exp Ther. 2001. PMID: 11160637

10

Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor.

Lee CH, Jiang M, Cowart M, Gfesser G, Perner R, Kim KH, Gu YG, Williams M, Jarvis MF, Kowaluk EA, Stewart AO, Bhagwat SS. Lee CH, et al. Among authors: jarvis mf. J Med Chem. 2001 Jun 21;44(13):2133-8. doi: 10.1021/jm000314x. J Med Chem. 2001. PMID: 11405650

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