Carr TJ - Search Results

1

Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K.

Marquis RW, Ru Y, Yamashita DS, Oh HJ, Yen J, Thompson SK, Carr TJ, Levy MA, Tomaszek TA, Ijames CF, Smith WW, Zhao B, Janson CA, Abdel-Meguid SS, D'Alessio KJ, McQueney MS, Veber DF. Marquis RW, et al. Among authors: carr tj. Bioorg Med Chem. 1999 Apr;7(4):581-8. doi: 10.1016/s0968-0896(99)00011-5. Bioorg Med Chem. 1999. PMID: 10353637

2

Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo.

Votta BJ, Levy MA, Badger A, Bradbeer J, Dodds RA, James IE, Thompson S, Bossard MJ, Carr T, Connor JR, Tomaszek TA, Szewczuk L, Drake FH, Veber DF, Gowen M. Votta BJ, et al. J Bone Miner Res. 1997 Sep;12(9):1396-406. doi: 10.1359/jbmr.1997.12.9.1396. J Bone Miner Res. 1997. PMID: 9286755 Free article.

3

Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites.

LaLonde JM, Zhao B, Smith WW, Janson CA, DesJarlais RL, Tomaszek TA, Carr TJ, Thompson SK, Oh HJ, Yamashita DS, Veber DF, Abdel-Meguid SS. LaLonde JM, et al. Among authors: carr tj. J Med Chem. 1998 Nov 5;41(23):4567-76. doi: 10.1021/jm980249f. J Med Chem. 1998. PMID: 9804696

4

Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.

Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA Jr, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M, et al. Dreyer GB, et al. Among authors: carr tj. Biochemistry. 1992 Jul 28;31(29):6646-59. doi: 10.1021/bi00144a004. Biochemistry. 1992. PMID: 1637805

5

Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors.

Dreyer GB, Metcalf BW, Tomaszek TA Jr, Carr TJ, Chandler AC 3rd, Hyland L, Fakhoury SA, Magaard VW, Moore ML, Strickler JE, et al. Dreyer GB, et al. Among authors: carr tj. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9752-6. doi: 10.1073/pnas.86.24.9752. Proc Natl Acad Sci U S A. 1989. PMID: 2690072 Free PMC article.

6

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues.

Meek TD, Lambert DM, Dreyer GB, Carr TJ, Tomaszek TA Jr, Moore ML, Strickler JE, Debouck C, Hyland LJ, Matthews TJ, et al. Meek TD, et al. Among authors: carr tj. Nature. 1990 Jan 4;343(6253):90-2. doi: 10.1038/343090a0. Nature. 1990. PMID: 1688646

7

An orally bioavailable HIV-1 protease inhibitor containing an imidazole-derived peptide bond replacement: crystallographic and pharmacokinetic analysis.

Abdel-Meguid SS, Metcalf BW, Carr TJ, Demarsh P, DesJarlais RL, Fisher S, Green DW, Ivanoff L, Lambert DM, Murthy KH, et al. Abdel-Meguid SS, et al. Among authors: carr tj. Biochemistry. 1994 Oct 4;33(39):11671-7. doi: 10.1021/bi00205a001. Biochemistry. 1994. PMID: 7918383

8

The relationship between hostility and blood pressure in children.

Treiber FA, Musante L, Riley W, Mabe PA, Carr T, Levy M, Strong WB. Treiber FA, et al. Behav Med. 1989 Winter;15(4):173-8. doi: 10.1080/08964289.1989.9934581. Behav Med. 1989. PMID: 2597781

9

Assessment of children's Type A behavior: relationship with negative behavioral characteristics and children and teacher demographic characteristics.

Treiber FA, Mabe PA 3rd, Riley W, Carr T, Levy M, Thompson W, Strong WB. Treiber FA, et al. J Pers Assess. 1989 Winter;53(4):770-82. doi: 10.1207/s15327752jpa5304_13. J Pers Assess. 1989. PMID: 2607405

10

RNA sequencing demonstrates large-scale temporal dysregulation of gene expression in stimulated macrophages derived from MHC-defined chicken haplotypes.

Irizarry KJL, Downs E, Bryden R, Clark J, Griggs L, Kopulos R, Boettger CM, Carr TJ Jr, Keeler CL, Collisson E, Drechsler Y. Irizarry KJL, et al. Among authors: carr tj jr. PLoS One. 2017 Aug 28;12(8):e0179391. doi: 10.1371/journal.pone.0179391. eCollection 2017. PLoS One. 2017. PMID: 28846708 Free PMC article.

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