Gray NS - Search Results

1

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Among authors: gray ns. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538

2

The immunological evolution of catalysis.

Patten PA, Gray NS, Yang PL, Marks CB, Wedemayer GJ, Boniface JJ, Stevens RC, Schultz PG. Patten PA, et al. Among authors: gray ns. Science. 1996 Feb 23;271(5252):1086-91. doi: 10.1126/science.271.5252.1086. Science. 1996. PMID: 8599084

3

CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation.

Brooks EE, Gray NS, Joly A, Kerwar SS, Lum R, Mackman RL, Norman TC, Rosete J, Rowe M, Schow SR, Schultz PG, Wang X, Wick MM, Shiffman D. Brooks EE, et al. Among authors: gray ns. J Biol Chem. 1997 Nov 14;272(46):29207-11. doi: 10.1074/jbc.272.46.29207. J Biol Chem. 1997. PMID: 9360999 Free article.

4

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190 Free article.

5

A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts.

Rosania GR, Merlie J Jr, Gray N, Chang YT, Schultz PG, Heald R. Rosania GR, et al. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4797-802. doi: 10.1073/pnas.96.9.4797. Proc Natl Acad Sci U S A. 1999. PMID: 10220373 Free PMC article.

6

ATP-site directed inhibitors of cyclin-dependent kinases.

Gray N, Détivaud L, Doerig C, Meijer L. Gray N, et al. Curr Med Chem. 1999 Sep;6(9):859-75. Curr Med Chem. 1999. PMID: 10495356 Review.

7

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

Knockaert M, Gray N, Damiens E, Chang YT, Grellier P, Grant K, Fergusson D, Mottram J, Soete M, Dubremetz JF, Le Roch K, Doerig C, Schultz P, Meijer L. Knockaert M, et al. Chem Biol. 2000 Jun;7(6):411-22. doi: 10.1016/s1074-5521(00)00124-1. Chem Biol. 2000. PMID: 10873834

8

A chemical switch for inhibitor-sensitive alleles of any protein kinase.

Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. Bishop AC, et al. Among authors: gray ns. Nature. 2000 Sep 21;407(6802):395-401. doi: 10.1038/35030148. Nature. 2000. PMID: 11014197

9

Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

Harmse L, van Zyl R, Gray N, Schultz P, Leclerc S, Meijer L, Doerig C, Havlik I. Harmse L, et al. Biochem Pharmacol. 2001 Aug 1;62(3):341-8. doi: 10.1016/s0006-2952(01)00644-x. Biochem Pharmacol. 2001. PMID: 11434907

10

Discovery of estrogen sulfotransferase inhibitors from a purine library screen.

Verdugo DE, Cancilla MT, Ge X, Gray NS, Chang YT, Schultz PG, Negishi M, Leary JA, Bertozzi CR. Verdugo DE, et al. Among authors: gray ns. J Med Chem. 2001 Aug 16;44(17):2683-6. doi: 10.1021/jm010171u. J Med Chem. 2001. PMID: 11495578 No abstract available.

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