Claassen GF - Search Results

1

Myc-mediated transformation: the repression connection.

Claassen GF, Hann SR. Claassen GF, et al. Oncogene. 1999 May 13;18(19):2925-33. doi: 10.1038/sj.onc.1202747. Oncogene. 1999. PMID: 10378689 Review.

2

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest.

Claassen GF, Hann SR. Claassen GF, et al. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9498-503. doi: 10.1073/pnas.150006697. Proc Natl Acad Sci U S A. 2000. PMID: 10920185 Free PMC article.

3

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis.

Xiao Q, Claassen G, Shi J, Adachi S, Sedivy J, Hann SR. Xiao Q, et al. Genes Dev. 1998 Dec 15;12(24):3803-8. doi: 10.1101/gad.12.24.3803. Genes Dev. 1998. PMID: 9869633 Free PMC article.

4

The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals.

Chang DW, Claassen GF, Hann SR, Cole MD. Chang DW, et al. Among authors: claassen gf. Mol Cell Biol. 2000 Jun;20(12):4309-19. doi: 10.1128/MCB.20.12.4309-4319.2000. Mol Cell Biol. 2000. PMID: 10825194 Free PMC article.

5

Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma.

Niklinski J, Claassen G, Meyers C, Gregory MA, Allegra CJ, Kaye FJ, Hann SR, Zajac-Kaye M. Niklinski J, et al. Mol Cell Biol. 2000 Jul;20(14):5276-84. doi: 10.1128/MCB.20.14.5276-5284.2000. Mol Cell Biol. 2000. PMID: 10866684 Free PMC article.

6

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D, Testa JE, Quigley JP. Hooper JD, et al. Among authors: claassen gf. Oncogene. 2003 Mar 27;22(12):1783-94. doi: 10.1038/sj.onc.1206220. Oncogene. 2003. PMID: 12660814

7

Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathway.

Claassen G, Brin E, Crogan-Grundy C, Vaillancourt MT, Zhang HZ, Cai SX, Drewe J, Tseng B, Kasibhatla S. Claassen G, et al. Cancer Lett. 2009 Feb 18;274(2):243-9. doi: 10.1016/j.canlet.2008.09.032. Epub 2008 Nov 12. Cancer Lett. 2009. PMID: 19008038

8

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.

Sirisoma N, Kasibhatla S, Nguyen B, Pervin A, Wang Y, Claassen G, Tseng B, Drewe J, Cai SX. Sirisoma N, et al. Bioorg Med Chem. 2006 Dec 1;14(23):7761-73. doi: 10.1016/j.bmc.2006.08.002. Epub 2006 Aug 21. Bioorg Med Chem. 2006. PMID: 16919962

9

Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers.

Zhang HZ, Claassen G, Crogran-Grundy C, Tseng B, Drewe J, Cai SX. Zhang HZ, et al. Bioorg Med Chem. 2008 Jan 1;16(1):222-31. doi: 10.1016/j.bmc.2007.09.046. Epub 2007 Oct 4. Bioorg Med Chem. 2008. PMID: 17950608

10

Synthesis, SAR and biological evaluation of 1,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidines as dual inhibitors of Aurora kinases and CDK1.

Le Brazidec JY, Pasis A, Tam B, Boykin C, Black C, Wang D, Claassen G, Chong JH, Chao J, Fan J, Nguyen K, Silvian L, Ling L, Zhang L, Choi M, Teng M, Pathan N, Zhao S, Li T, Taveras A. Le Brazidec JY, et al. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2070-4. doi: 10.1016/j.bmcl.2012.01.019. Epub 2012 Jan 18. Bioorg Med Chem Lett. 2012. PMID: 22326168

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