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A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy.
Lindenbaum M, Perkins E, Csonka E, Fleming E, Garcia L, Greene A, Gung L, Hadlaczky G, Lee E, Leung J, MacDonald N, Maxwell A, Mills K, Monteith D, Perez CF, Shellard J, Stewart S, Stodola T, Vandenborre D, Vanderbyl S, Ledebur HC Jr. Lindenbaum M, et al. Among authors: ledebur hc jr. Nucleic Acids Res. 2004 Dec 7;32(21):e172. doi: 10.1093/nar/gnh169. Nucleic Acids Res. 2004. PMID: 15585659 Free PMC article.
Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs.
Smith DH, Burrell JC, Browne KD, Katiyar KS, Ezra MI, Dutton JL, Morand JP, Struzyna LA, Laimo FA, Chen HI, Wolf JA, Kaplan HM, Rosen JM, Ledebur HC, Zager EL, Ali ZS, Cullen DK. Smith DH, et al. Among authors: ledebur hc. Sci Adv. 2022 Nov 4;8(44):eabm3291. doi: 10.1126/sciadv.abm3291. Epub 2022 Nov 4. Sci Adv. 2022. PMID: 36332027 Free PMC article.
Innervation: the missing link for biofabricated tissues and organs.
Das S, Gordián-Vélez WJ, Ledebur HC, Mourkioti F, Rompolas P, Chen HI, Serruya MD, Cullen DK. Das S, et al. Among authors: ledebur hc. NPJ Regen Med. 2020 Jun 5;5:11. doi: 10.1038/s41536-020-0096-1. eCollection 2020. NPJ Regen Med. 2020. PMID: 32550009 Free PMC article. Review.
15 results