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Page 1
Some of the amino acid chemistry going on in the Laboratory of Amino Acids, Peptides and Proteins.
Bouifraden S, Drouot C, el Hadrami M, Guenoun F, Lecointe L, Mai N, Paris M, Pothion C, Sadoune M, Sauvagnat B, Amblard M, Aubagnac JL, Calmes M, Chevallet P, Daunis J, Enjalbal C, Fehrentz JA, Lamaty F, Lavergne JP, Lazaro R, Rolland V, Roumestant ML, Viallefont P, Vidal Y, Martinez J. Bouifraden S, et al. Among authors: sauvagnat b. Amino Acids. 1999;16(3-4):345-79. doi: 10.1007/BF01388176. Amino Acids. 1999. PMID: 10399020 Review.
Chemical reactivity in matrix-assisted laser desorption/ionization mass spectrometry.
Enjalbal C, Sauvagnat B, Lamaty F, Lazaro R, Martinez J, Mouchet P, Roux F, Aubagnac J. Enjalbal C, et al. Among authors: sauvagnat b. Rapid Commun Mass Spectrom. 1999;13(18):1775-81. doi: 10.1002/(SICI)1097-0231(19990930)13:18<1775::AID-RCM712>3.0.CO;2-U. Rapid Commun Mass Spectrom. 1999. PMID: 10482888
Rapid Affinity and Microsomal Stability Ranking of Crude Mixture Libraries of Histone Deacetylase Inhibitors.
Tyagarajan S, Andrews CL, Beshore DC, Buevich AV, Curran PJ, Dandliker P, Greshock TJ, Hoar J, Kim A, Karnachi P, Knemeyer I, Kozlowski J, Liu J, Maletic M, Myers R, Rada V, Sha D, Sauvagnat B, Vachal P, Wolkenberg S, Yu W, Yu Y, Krska SW. Tyagarajan S, et al. Among authors: sauvagnat b. ACS Med Chem Lett. 2024 Sep 12;15(10):1787-1794. doi: 10.1021/acsmedchemlett.4c00345. eCollection 2024 Oct 10. ACS Med Chem Lett. 2024. PMID: 39411537
Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) Technology.
Garrigou M, Sauvagnat B, Duggal R, Boo N, Gopal P, Johnston JM, Partridge A, Sawyer T, Biswas K, Boyer N. Garrigou M, et al. Among authors: sauvagnat b. J Med Chem. 2022 Jul 14;65(13):8961-8974. doi: 10.1021/acs.jmedchem.2c00154. Epub 2022 Jun 15. J Med Chem. 2022. PMID: 35707970 Free PMC article.
An orally available non-nucleotide STING agonist with antitumor activity.
Pan BS, Perera SA, Piesvaux JA, Presland JP, Schroeder GK, Cumming JN, Trotter BW, Altman MD, Buevich AV, Cash B, Cemerski S, Chang W, Chen Y, Dandliker PJ, Feng G, Haidle A, Henderson T, Jewell J, Kariv I, Knemeyer I, Kopinja J, Lacey BM, Laskey J, Lesburg CA, Liang R, Long BJ, Lu M, Ma Y, Minnihan EC, O'Donnell G, Otte R, Price L, Rakhilina L, Sauvagnat B, Sharma S, Tyagarajan S, Woo H, Wyss DF, Xu S, Bennett DJ, Addona GH. Pan BS, et al. Among authors: sauvagnat b. Science. 2020 Aug 21;369(6506):eaba6098. doi: 10.1126/science.aba6098. Science. 2020. PMID: 32820094
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.
Siu T, Altman MD, Baltus GA, Childers M, Ellis JM, Gunaydin H, Hatch H, Ho T, Jewell J, Lacey BM, Lesburg CA, Pan BS, Sauvagnat B, Schroeder GK, Xu S. Siu T, et al. Among authors: sauvagnat b. ACS Med Chem Lett. 2018 Dec 6;10(1):92-97. doi: 10.1021/acsmedchemlett.8b00466. eCollection 2019 Jan 10. ACS Med Chem Lett. 2018. PMID: 30655953 Free PMC article.
Nanoscale synthesis and affinity ranking.
Gesmundo NJ, Sauvagnat B, Curran PJ, Richards MP, Andrews CL, Dandliker PJ, Cernak T. Gesmundo NJ, et al. Among authors: sauvagnat b. Nature. 2018 May;557(7704):228-232. doi: 10.1038/s41586-018-0056-8. Epub 2018 Apr 23. Nature. 2018. PMID: 29686415
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