Sanguinetti MC - Search Results

1

Long QT syndrome-associated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits.

Franqueza L, Lin M, Shen J, Splawski I, Keating MT, Sanguinetti MC. Franqueza L, et al. Among authors: sanguinetti mc. J Biol Chem. 1999 Jul 23;274(30):21063-70. doi: 10.1074/jbc.274.30.21063. J Biol Chem. 1999. PMID: 10409658 Free article.

2

Compound mutations: a common cause of severe long-QT syndrome.

Westenskow P, Splawski I, Timothy KW, Keating MT, Sanguinetti MC. Westenskow P, et al. Among authors: sanguinetti mc. Circulation. 2004 Apr 20;109(15):1834-41. doi: 10.1161/01.CIR.0000125524.34234.13. Epub 2004 Mar 29. Circulation. 2004. PMID: 15051636

3

Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.

Spector PS, Curran ME, Keating MT, Sanguinetti MC. Spector PS, et al. Among authors: sanguinetti mc. Circ Res. 1996 Mar;78(3):499-503. doi: 10.1161/01.res.78.3.499. Circ Res. 1996. PMID: 8593709

4

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.

Sanguinetti MC, Curran ME, Spector PS, Keating MT. Sanguinetti MC, et al. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2208-12. doi: 10.1073/pnas.93.5.2208. Proc Natl Acad Sci U S A. 1996. PMID: 8700910 Free PMC article.

5

Pathophysiology of ion channel mutations.

Keating MT, Sanguinetti MC. Keating MT, et al. Among authors: sanguinetti mc. Curr Opin Genet Dev. 1996 Jun;6(3):326-33. doi: 10.1016/s0959-437x(96)80010-4. Curr Opin Genet Dev. 1996. PMID: 8791523 Review.

6

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel.

Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT. Sanguinetti MC, et al. Nature. 1996 Nov 7;384(6604):80-3. doi: 10.1038/384080a0. Nature. 1996. PMID: 8900283

7

Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes.

Zou A, Curran ME, Keating MT, Sanguinetti MC. Zou A, et al. Among authors: sanguinetti mc. Am J Physiol. 1997 Mar;272(3 Pt 2):H1309-14. doi: 10.1152/ajpheart.1997.272.3.H1309. Am J Physiol. 1997. PMID: 9087606

8

Mutations in the hminK gene cause long QT syndrome and suppress IKs function.

Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC, Keating MT. Splawski I, et al. Among authors: sanguinetti mc. Nat Genet. 1997 Nov;17(3):338-40. doi: 10.1038/ng1197-338. Nat Genet. 1997. PMID: 9354802

9

Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.

Chen J, Zou A, Splawski I, Keating MT, Sanguinetti MC. Chen J, et al. Among authors: sanguinetti mc. J Biol Chem. 1999 Apr 9;274(15):10113-8. doi: 10.1074/jbc.274.15.10113. J Biol Chem. 1999. PMID: 10187793 Free article.

10

Functional effects of mutations in KvLQT1 that cause long QT syndrome.

Wang Z, Tristani-Firouzi M, Xu Q, Lin M, Keating MT, Sanguinetti MC. Wang Z, et al. Among authors: sanguinetti mc. J Cardiovasc Electrophysiol. 1999 Jun;10(6):817-26. doi: 10.1111/j.1540-8167.1999.tb00262.x. J Cardiovasc Electrophysiol. 1999. PMID: 10376919

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