Koch WJ - Search Results

1

Defective beta-adrenergic receptor signaling precedes the development of dilated cardiomyopathy in transgenic mice with calsequestrin overexpression.

Cho MC, Rapacciuolo A, Koch WJ, Kobayashi Y, Jones LR, Rockman HA. Cho MC, et al. Among authors: koch wj. J Biol Chem. 1999 Aug 6;274(32):22251-6. doi: 10.1074/jbc.274.32.22251. J Biol Chem. 1999. PMID: 10428792 Free article.

2

Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure.

Eckhart AD, Ozaki T, Tevaearai H, Rockman HA, Koch WJ. Eckhart AD, et al. Among authors: koch wj. Mol Pharmacol. 2002 Apr;61(4):749-58. doi: 10.1124/mol.61.4.749. Mol Pharmacol. 2002. PMID: 11901213

3

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

Feldman DS, Zamah AM, Pierce KL, Miller WE, Kelly F, Rapacciuolo A, Rockman HA, Koch WJ, Luttrell LM. Feldman DS, et al. Among authors: koch wj. J Biol Chem. 2002 Aug 9;277(32):28631-40. doi: 10.1074/jbc.M204753200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036966 Free article.

4

Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase.

Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Choi DJ, et al. Among authors: koch wj. J Biol Chem. 1997 Jul 4;272(27):17223-9. doi: 10.1074/jbc.272.27.17223. J Biol Chem. 1997. PMID: 9202046 Free article.

5

Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling.

Akhter SA, Milano CA, Shotwell KF, Cho MC, Rockman HA, Lefkowitz RJ, Koch WJ. Akhter SA, et al. Among authors: koch wj. J Biol Chem. 1997 Aug 22;272(34):21253-9. doi: 10.1074/jbc.272.34.21253. J Biol Chem. 1997. PMID: 9261135 Free article.

6

Myocardial overexpression of adrenergic receptors and receptor kinases.

Koch WJ, Lefkowitz RJ, Milano CA, Akhter SA, Rockman HA. Koch WJ, et al. Adv Pharmacol. 1998;42:502-6. doi: 10.1016/s1054-3589(08)60799-1. Adv Pharmacol. 1998. PMID: 9327950 No abstract available.

7

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice.

Rockman HA, Chien KR, Choi DJ, Iaccarino G, Hunter JJ, Ross J Jr, Lefkowitz RJ, Koch WJ. Rockman HA, et al. Among authors: koch wj. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7000-5. doi: 10.1073/pnas.95.12.7000. Proc Natl Acad Sci U S A. 1998. PMID: 9618528 Free PMC article.

8

Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice.

Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Rockman HA, et al. Among authors: koch wj. J Biol Chem. 1998 Jul 17;273(29):18180-4. doi: 10.1074/jbc.273.29.18180. J Biol Chem. 1998. PMID: 9660778 Free article.

9

Myocardial overexpression of GRK3 in transgenic mice: evidence for in vivo selectivity of GRKs.

Iaccarino G, Rockman HA, Shotwell KF, Tomhave ED, Koch WJ. Iaccarino G, et al. Among authors: koch wj. Am J Physiol. 1998 Oct;275(4):H1298-306. doi: 10.1152/ajpheart.1998.275.4.H1298. Am J Physiol. 1998. PMID: 9746479

10

Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.

Cho MC, Rao M, Koch WJ, Thomas SA, Palmiter RD, Rockman HA. Cho MC, et al. Among authors: koch wj. Circulation. 1999 May 25;99(20):2702-7. doi: 10.1161/01.cir.99.20.2702. Circulation. 1999. PMID: 10338466

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