Wiltrout RH - Search Results

1

Intradermal delivery of IL-12 naked DNA induces systemic NK cell activation and Th1 response in vivo that is independent of endogenous IL-12 production.

Watanabe M, Fenton RG, Wigginton JM, McCormick KL, Volker KM, Fogler WE, Roessler PG, Wiltrout RH. Watanabe M, et al. Among authors: wiltrout rh. J Immunol. 1999 Aug 15;163(4):1943-50. J Immunol. 1999. PMID: 10438930

2

Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2.

Wigginton JM, Lee JK, Wiltrout TA, Alvord WG, Hixon JA, Subleski J, Back TC, Wiltrout RH. Wigginton JM, et al. Among authors: wiltrout rh, wiltrout ta. J Immunol. 2002 Oct 15;169(8):4467-74. doi: 10.4049/jimmunol.169.8.4467. J Immunol. 2002. PMID: 12370382

3

In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells.

Ortaldo JR, Winkler-Pickett RT, Bere EW Jr, Watanabe M, Murphy WJ, Wiltrout RH. Ortaldo JR, et al. Among authors: wiltrout rh. J Immunol. 2005 Jul 15;175(2):693-9. doi: 10.4049/jimmunol.175.2.693. J Immunol. 2005. PMID: 16002664

4

TNF-alpha is a principal cytokine involved in the recruitment of NK cells to liver parenchyma.

Pilaro AM, Taub DD, McCormick KL, Williams HM, Sayers TJ, Fogler WE, Wiltrout RH. Pilaro AM, et al. Among authors: wiltrout rh. J Immunol. 1994 Jul 1;153(1):333-42. J Immunol. 1994. PMID: 8207246

5

NK cell infiltration into lung, liver, and subcutaneous B16 melanoma is mediated by VCAM-1/VLA-4 interaction.

Fogler WE, Volker K, McCormick KL, Watanabe M, Ortaldo JR, Wiltrout RH. Fogler WE, et al. Among authors: wiltrout rh. J Immunol. 1996 Jun 15;156(12):4707-14. J Immunol. 1996. PMID: 8648116

6

T cell- and NK cell-independent inhibition of hepatic metastases by systemic administration of an IL-12-expressing recombinant adenovirus.

Siders WM, Wright PW, Hixon JA, Alvord WG, Back TC, Wiltrout RH, Fenton RG. Siders WM, et al. Among authors: wiltrout rh. J Immunol. 1998 Jun 1;160(11):5465-74. J Immunol. 1998. PMID: 9605149

7

Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells.

Sayers TJ, Brooks AD, Lee JK, Fenton RG, Komschlies KL, Wigginton JM, Winkler-Pickett R, Wiltrout RH. Sayers TJ, et al. Among authors: wiltrout rh. J Immunol. 1998 Oct 15;161(8):3957-65. J Immunol. 1998. PMID: 9780164

8

Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas.

Fogler WE, Volker K, Watanabe M, Wigginton JM, Roessler P, Brunda MJ, Ortaldo JR, Wiltrout RH. Fogler WE, et al. Among authors: wiltrout rh. J Immunol. 1998 Dec 1;161(11):6014-21. J Immunol. 1998. PMID: 9834083

9

IFN-gamma-dependent delay of in vivo tumor progression by Fas overexpression on murine renal cancer cells.

Lee JK, Sayers TJ, Brooks AD, Back TC, Young HA, Komschlies KL, Wigginton JM, Wiltrout RH. Lee JK, et al. Among authors: wiltrout rh. J Immunol. 2000 Jan 1;164(1):231-9. doi: 10.4049/jimmunol.164.1.231. J Immunol. 2000. PMID: 10605016

10

Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis.

Wigginton JM, Park JW, Gruys ME, Young HA, Jorcyk CL, Back TC, Brunda MJ, Strieter RM, Ward J, Green JE, Wiltrout RH. Wigginton JM, et al. Among authors: wiltrout rh. J Immunol. 2001 Jan 15;166(2):1156-68. doi: 10.4049/jimmunol.166.2.1156. J Immunol. 2001. PMID: 11145697

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