Scozzafava A - Search Results

1

Carbonic anhydrase inhibitors: N-cyanosulfonamides, a new class of high affinity isozyme II and IV inhibitors.

Supuran CT, Scozzafava A, Briganti F. Supuran CT, et al. Among authors: scozzafava a. J Enzyme Inhib. 1999;14(4):289-306. doi: 10.3109/14756369909030323. J Enzyme Inhib. 1999. PMID: 10445050

2

Carbonic anhydrase activators: high affinity isozymes I, II, and IV activators, incorporating a beta-alanyl-histidine scaffold.

Scozzafava A, Supuran CT. Scozzafava A, et al. J Med Chem. 2002 Jan 17;45(2):284-91. doi: 10.1021/jm010958k. J Med Chem. 2002. PMID: 11784133

3

Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

Scozzafava A, Menabuoni L, Mincione F, Supuran CT. Scozzafava A, et al. J Med Chem. 2002 Mar 28;45(7):1466-76. doi: 10.1021/jm0108202. J Med Chem. 2002. PMID: 11906288

4

Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1.

Scozzafava A, Supuran CT. Scozzafava A, et al. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1177-80. doi: 10.1016/s0960-894x(02)00121-x. Bioorg Med Chem Lett. 2002. PMID: 11934582

5

Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination.

Ferraroni M, Tilli S, Briganti F, Chegwidden WR, Supuran CT, Wiebauer KE, Tashian RE, Scozzafava A. Ferraroni M, et al. Among authors: scozzafava a. Biochemistry. 2002 May 21;41(20):6237-44. doi: 10.1021/bi0120446. Biochemistry. 2002. PMID: 12009884

6

Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.

Scozzafava A, Supuran CT. Scozzafava A, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1551-7. doi: 10.1016/s0960-894x(02)00252-4. Bioorg Med Chem Lett. 2002. PMID: 12039560

7

Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design.

Abbate F, Supuran CT, Scozzafava A, Orioli P, Stubbs MT, Klebe G. Abbate F, et al. Among authors: scozzafava a. J Med Chem. 2002 Aug 15;45(17):3583-7. doi: 10.1021/jm011131t. J Med Chem. 2002. PMID: 12166931

8

Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents.

Maestrelli F, Mura P, Casini A, Mincione F, Scozzafava A, Supuran CT. Maestrelli F, et al. Among authors: scozzafava a. J Pharm Sci. 2002 Oct;91(10):2211-9. doi: 10.1002/jps.10215. J Pharm Sci. 2002. PMID: 12226848

9

Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold.

Casini A, Mincione F, Vullo D, Menabuoni L, Scozzafava A, Supuran CT. Casini A, et al. Among authors: scozzafava a. J Enzyme Inhib Med Chem. 2002 Feb;17(1):9-18. doi: 10.1080/14756360290018602. J Enzyme Inhib Med Chem. 2002. PMID: 12365464 Free article.

10

Non-peptidic chemokine receptors antagonists as emerging anti-HIV agents.

Scozzafava A, Mastrolorenzo A, Supuran CT. Scozzafava A, et al. J Enzyme Inhib Med Chem. 2002 Apr;17(2):69-76. doi: 10.1080/14756360290024227. J Enzyme Inhib Med Chem. 2002. PMID: 12420752 Free article. Review.

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